Journal ArticleDOI
Estimation of dehydroascorbic acid in blood of diabetic patients
I. B. Chatterjee,A. Banerjee +1 more
TLDR
The DHA from diabetic blood has been isolated as the 2,4-dinitrophenylhydrazone derivative and identified by thin-layer chromatography and spectrophotometry.About:
This article is published in Analytical Biochemistry.The article was published on 1979-10-01. It has received 77 citations till now. The article focuses on the topics: Dehydroascorbic acid & Ascorbic acid.read more
Citations
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Journal ArticleDOI
Effects of cytochalasin B on the uptake of ascorbic acid and glucose by 3T3 fibroblasts: mechanism of impaired ascorbate transport in diabetes.
TL;DR: The present studies show that the glucose transport inhibitor cytochalasin B blocked the uptake of 3H-2-deoxy-D-glucose by mouse 3T3 fibroblasts, supporting the hypothesis that glucose and ascorbate share a common transport system.
Journal ArticleDOI
Effect of monosaccharide on dehydroascorbic acid uptake by placental membrane vesicles.
TL;DR: The results suggest that moderate maternal hyperglycemia does not alter, but that severe hypo- or hyper glycemia decreases, placental uptake of DHA from the maternal circulation.
Journal ArticleDOI
Plasma levels of vitamin C components in normal and diabetic subjects.
TL;DR: No evidence that diabetic patients have higher plasma dehydroascorbic acid levels than nondiabetics is found, and some possible reasons are considered for the discrepancy between this finding and those of earlier reports.
Journal ArticleDOI
Ascorbic acid repletion: A possible therapy for diabetic macular edema?
TL;DR: Cell culture studies show that the vitamin prevents high-glucose and RAGE-induced apoptosis in both cell types, that it preserves nitric oxide generated by endothelial cells, and that it tightens the leaky endothelial permeability barrier.
Journal ArticleDOI
Ascorbic acid modulation of calcium channels in pancreatic beta cells.
R V Parsey,D R Matteson +1 more
TL;DR: It is shown that the slowly deactivating (SD) calcium channel, which is similar to the T-type channel in other cells, is inhibited in a voltage-dependent manner by ascorbic acid, while the other channels that carry inward current in pancreatic beta cells, FD calcium channels and sodium channels, are unaffected by AA.
References
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Book
Methods of Enzymatic Analysis
TL;DR: Methods of enzymatic analysis, Methods of enzymes analysis, the authors, Methods of enzyme analysis, enzymatics, methods of enzymes, and methods of analysis, method of enzymes.
Journal ArticleDOI
Synthesis and some major functions of vitamin C in animals.
TL;DR: Using the in vitro method, the ascorbic acid synthesizing abilities of different species of animals in the phylogenetic tree are examined, and the results are given below.
Journal ArticleDOI
The determination of diketo l-gulonic acid, dehydro-l-ascorbic acid, and l-ascorbic acid in the same tissue extract by the 2, 4-dinitrophenylhydrazine method.
TL;DR: Methods for determinations of vitamin C dehydro-Z-ascorbic (DHA), DHA, and DKA in the presence of each other are reported, indicating that these derivatives are identical substances.
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The use of homocysteine in the estimation of dehydroascorbic acid.
TL;DR: An account is given of a new method, based on the two findings that homocysteine rapidly reduces dehydroascorbic acid at pH 7 0, and that under certain simple conditions 2:6-dichlorophenolindophenol can be used to estimate ascorbic acid in the presence of homocy steine without interference from the latter compound.