Journal ArticleDOI
Estimation of dehydroascorbic acid in blood of diabetic patients
I. B. Chatterjee,A. Banerjee +1 more
TLDR
The DHA from diabetic blood has been isolated as the 2,4-dinitrophenylhydrazone derivative and identified by thin-layer chromatography and spectrophotometry.About:
This article is published in Analytical Biochemistry.The article was published on 1979-10-01. It has received 77 citations till now. The article focuses on the topics: Dehydroascorbic acid & Ascorbic acid.read more
Citations
More filters
Journal ArticleDOI
A specific high-performance liquid chromatography assay for dehydroascorbic acid shows an increased content in CLL lymphocytes.
TL;DR: These studies illustrate that the technique can be used to measure the dehydroascorbic acid content from sources where only scanty material is available or low levels are found, and that the elevated level in chronic lymphocytic leukemia was not simply a reflection of the increased percentage of B lymphocytes in this disorder.
Journal ArticleDOI
Advanced Maillard reaction products as markers for tissue damage in diabetes and uraemia: relevance to diabetic nephropathy
Vincent M. Monnier,David R. Sell,Satoshi Miyata,Ramanakoppa H. Nagaraj,Patrizio Odetti,Annuziata Lapolla +5 more
TL;DR: Pyrraline, pentosidine and carboxymethyllysine can serve as markers for in vivo studies as discussed by the authors, and their levels correlate with the severity of diabetic complications in type I (insulin dependent) diabetes.
Journal ArticleDOI
Inhibition of aldose reductase in human erythrocytes by vitamin C.
TL;DR: Results show that high, but physiologic, concentrations of ascorbic acid can directly inhibit erythrocyte aldose reductase, and provide a rationale for the use of oral vitamin C supplements in diabetes.
Journal ArticleDOI
Redox Regulation of Hexokinases.
TL;DR: Modulation of hexokinase activity and spatiotemporal location by reactive oxygen and nitrogen species as well as other gasotransmitters serves as the basis for a unique, underexplored method of tight and flexible regulation of these fundamental enzymes.
Journal ArticleDOI
Formation constants of copper(I) complexes with cysteine, penicillamine and glutathione: implications for copper speciation in the human eye
TL;DR: This simulation provided an explanation for the precipitation of metallic copper in lens and cornea, and was used to predict, for the first time, metal-ligand equilibria in the biofluids of the human eye.
References
More filters
Book
Methods of Enzymatic Analysis
TL;DR: Methods of enzymatic analysis, Methods of enzymes analysis, the authors, Methods of enzyme analysis, enzymatics, methods of enzymes, and methods of analysis, method of enzymes.
Journal ArticleDOI
Synthesis and some major functions of vitamin C in animals.
TL;DR: Using the in vitro method, the ascorbic acid synthesizing abilities of different species of animals in the phylogenetic tree are examined, and the results are given below.
Journal ArticleDOI
The determination of diketo l-gulonic acid, dehydro-l-ascorbic acid, and l-ascorbic acid in the same tissue extract by the 2, 4-dinitrophenylhydrazine method.
TL;DR: Methods for determinations of vitamin C dehydro-Z-ascorbic (DHA), DHA, and DKA in the presence of each other are reported, indicating that these derivatives are identical substances.
Journal ArticleDOI
The use of homocysteine in the estimation of dehydroascorbic acid.
TL;DR: An account is given of a new method, based on the two findings that homocysteine rapidly reduces dehydroascorbic acid at pH 7 0, and that under certain simple conditions 2:6-dichlorophenolindophenol can be used to estimate ascorbic acid in the presence of homocy steine without interference from the latter compound.