Journal ArticleDOI
Estrogenic terpenes and terpenoids: Pathways, functions and applications.
TLDR
Applications of estrogenic terpenes and terpenoids are categorized into cancer treatment and prevention, cardioprotection, endocrine toxicity/reproductive dysfunction, food/supplement/traditional medicine, immunology/inflammation, menopausal syndromes and neuroprotection, where their benefits are discussed based on their availability, stability and variations.About:
This article is published in European Journal of Pharmacology.The article was published on 2017-11-15. It has received 55 citations till now. The article focuses on the topics: Terpene & Terpenoid.read more
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Antioxidant and antibacterial activity of seven predominant terpenoids
TL;DR: In this article, the efficacy of seven predominant wine terpenoids (i.e. α-pinene, limonene, myrcene, geraniol, linalool, nerol, and terpineol) against foodborne pathogenic bac...
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Nutritional implications of ginger: chemistry, biological activities and signaling pathways.
TL;DR: The molecular mechanisms of estrogen actions induced by ginger constituents and related applications, such as the chemoprevention of cancers, and the improvement of menopausal syndromes, osteoporosis, endometriosis, prostatic hyperplasia, polycystic ovary syndrome and Alzheimer's disease, were summarized by a comprehensive search of references.
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Ionic Liquid Solutions as a Green Tool for the Extraction and Isolation of Natural Products.
Jiao Xiao,Gang Chen,Ning Li +2 more
TL;DR: The application of ILs to rich the extraction of critical bioactive constituents that were reported possessing multiple therapeutic effects or pharmacological activities, from medicinal plants are described to further reduce the environmental damage caused by large quantity of organic chemical reagents.
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Kinetics of mace (Myristicae arillus) essential oil extraction using microwave assisted hydrodistillation: Effect of microwave power
TL;DR: In this paper, the main components of the essential oil obtained from hydrodistillation were beta pinene, alpha pinene and myristicin, 4-terpineol, and gamma terpinene.
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Monoterpenes modulating autophagy: A review study.
TL;DR: The effects of monoterpenes on autophagy and its relationship with therapeutic impacts of monoterspenes are discussed in the present MiniReview.
References
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Expression Profiling of Estrogen Responsive Genes Using Genomic and Proteomic Techniques for the Evaluation of Endocrine Disruptors
Masao Tanji,Ryoiti Kiyama +1 more
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Estrogenic effects of ginsenoside Rg1 in endometrial cells in vitro were not observed in immature CD-1 mice or ovariectomized mice model.
TL;DR: The results suggest that the estrogenic effects of Rg1 are distinct from those of estradiol and are cell type and tissue selective, as well as in heart and brain tissues in vivo.
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Effect of Vinca alkaloids on ERα levels and estradiol-induced responses in MCF-7 cells
Carlos Martínez-Campa,Pedro Casado,Rene Rodriguez,Pedro Zuazua,Juana M. García-Pedrero,Pedro S. Lazo,Sofía Ramos +6 more
TL;DR: It is demonstrated that in the breast cancer cell-line MCF-7, E2-induced proliferation before VAs treatment enhances the apoptotical response to VAs which might have important implications in clinica.
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Exploring the molecular basis of action of ring D aromatic steroidal antiestrogens.
TL;DR: Using molecular dynamics simulation, the binding mode of the natural salpichrolide A and a synthetic analog with an aromatic D ring within the ERα is modeled and it is found that a preferred inverted orientation of the steroids in the ligand‐binding pocket with the aromatic ring D occupying a position similar to that observed for the A ring of estradiol.
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Soyasaponin Bh, a triterpene saponin containing a unique hemiacetal-functional five-membered ring from Glycine max (soybeans).
TL;DR: An oleanane triterpenoid saponin, soyasaponin Bh containing a unique five-membered ring with a hemiacetal functionality together with seven known saponins were isolated from soybeans, showing a weak estrogenic effect in the yeast estrogen screen (YES) assay.