Journal ArticleDOI
Estrogenic terpenes and terpenoids: Pathways, functions and applications.
TLDR
Applications of estrogenic terpenes and terpenoids are categorized into cancer treatment and prevention, cardioprotection, endocrine toxicity/reproductive dysfunction, food/supplement/traditional medicine, immunology/inflammation, menopausal syndromes and neuroprotection, where their benefits are discussed based on their availability, stability and variations.About:
This article is published in European Journal of Pharmacology.The article was published on 2017-11-15. It has received 55 citations till now. The article focuses on the topics: Terpene & Terpenoid.read more
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Antioxidant and antibacterial activity of seven predominant terpenoids
TL;DR: In this article, the efficacy of seven predominant wine terpenoids (i.e. α-pinene, limonene, myrcene, geraniol, linalool, nerol, and terpineol) against foodborne pathogenic bac...
Journal ArticleDOI
Nutritional implications of ginger: chemistry, biological activities and signaling pathways.
TL;DR: The molecular mechanisms of estrogen actions induced by ginger constituents and related applications, such as the chemoprevention of cancers, and the improvement of menopausal syndromes, osteoporosis, endometriosis, prostatic hyperplasia, polycystic ovary syndrome and Alzheimer's disease, were summarized by a comprehensive search of references.
Journal ArticleDOI
Ionic Liquid Solutions as a Green Tool for the Extraction and Isolation of Natural Products.
Jiao Xiao,Gang Chen,Ning Li +2 more
TL;DR: The application of ILs to rich the extraction of critical bioactive constituents that were reported possessing multiple therapeutic effects or pharmacological activities, from medicinal plants are described to further reduce the environmental damage caused by large quantity of organic chemical reagents.
Journal ArticleDOI
Kinetics of mace (Myristicae arillus) essential oil extraction using microwave assisted hydrodistillation: Effect of microwave power
TL;DR: In this paper, the main components of the essential oil obtained from hydrodistillation were beta pinene, alpha pinene and myristicin, 4-terpineol, and gamma terpinene.
Journal ArticleDOI
Monoterpenes modulating autophagy: A review study.
TL;DR: The effects of monoterpenes on autophagy and its relationship with therapeutic impacts of monoterspenes are discussed in the present MiniReview.
References
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Dietary tocopherols inhibit cell proliferation, regulate expression of ERα, PPARγ and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia
Amanda K. Smolarek,Jae Young So,Paul E. Thomas,Hong Jin Lee,Hong Jin Lee,Shiby Paul,Anne Dombrowski,Chung Xiou Wang,Constance Lay Lay Saw,Tin Oo Khor,Ah-Ng Tony Kong,Kenneth R. Reuhl,Mao Jung Lee,Chung S. Yang,Nanjoo Suh +14 more
TL;DR: Greek TmT was shown to suppress inflammatory markers, inhibit E2‐induced cell proliferation, and upregulate PPARγ and Nrf2 expression in mammary hyperplasia, suggesting that γ‐TmT may be a promising agent for human breast cancer prevention.
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Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells
TL;DR: The results show that artemisinin switches proliferative human breast cancer cells from expressing a high ERalpha:ERbeta ratio to a condition in which ERbeta predominates, which parallels the physiological state linked to antiproliferative events in normal mammary epithelium.
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Ginsenoside Rg1 protects against 6‐OHDA‐induced neurotoxicity in neuroblastoma SK‐N‐SH cells via IGF‐I receptor and estrogen receptor pathways
TL;DR: The results suggest that ginsenoside Rg1 may attenuate 6‐OHDA‐induced apoptosis and its action might involve the activation of IGF‐IR signaling pathway and ER signaling pathway.
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Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells
Kar Wah Leung,Kar Wah Leung,Fung Ping Leung,Nai Ki Mak,Joyce Tombran-Tink,Joyce Tombran-Tink,Yu Huang,Ricky N S Wong +7 more
TL;DR: Whether two metabolites of ginsenoside, protopanaxadiol (g‐PPD) and protopAnaxatriol ( g‐PPT), could modulate endothelial cell functions through the glucocorticoid receptor (GR) and oestrogen receptor (ER) is examined.
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The effect of 17β-estradiol on IL-6 secretion and NF-κB DNA-binding activity in human retinal pigment epithelial cells
Tuomas Paimela,Tuomas Ryhänen,Eliisa Mannermaa,Johanna Ojala,Giedrius Kalesnykas,Antero Salminen,Kai Kaarniranta +6 more
TL;DR: The results indicate that IL-6 expression is regulated through NF-κB transcription factor and stereoid-receptor signalling pathways in ARPE-19 cells.