Journal ArticleDOI
Estrogenic terpenes and terpenoids: Pathways, functions and applications.
TLDR
Applications of estrogenic terpenes and terpenoids are categorized into cancer treatment and prevention, cardioprotection, endocrine toxicity/reproductive dysfunction, food/supplement/traditional medicine, immunology/inflammation, menopausal syndromes and neuroprotection, where their benefits are discussed based on their availability, stability and variations.About:
This article is published in European Journal of Pharmacology.The article was published on 2017-11-15. It has received 55 citations till now. The article focuses on the topics: Terpene & Terpenoid.read more
Citations
More filters
Journal ArticleDOI
Antioxidant and antibacterial activity of seven predominant terpenoids
TL;DR: In this article, the efficacy of seven predominant wine terpenoids (i.e. α-pinene, limonene, myrcene, geraniol, linalool, nerol, and terpineol) against foodborne pathogenic bac...
Journal ArticleDOI
Nutritional implications of ginger: chemistry, biological activities and signaling pathways.
TL;DR: The molecular mechanisms of estrogen actions induced by ginger constituents and related applications, such as the chemoprevention of cancers, and the improvement of menopausal syndromes, osteoporosis, endometriosis, prostatic hyperplasia, polycystic ovary syndrome and Alzheimer's disease, were summarized by a comprehensive search of references.
Journal ArticleDOI
Ionic Liquid Solutions as a Green Tool for the Extraction and Isolation of Natural Products.
Jiao Xiao,Gang Chen,Ning Li +2 more
TL;DR: The application of ILs to rich the extraction of critical bioactive constituents that were reported possessing multiple therapeutic effects or pharmacological activities, from medicinal plants are described to further reduce the environmental damage caused by large quantity of organic chemical reagents.
Journal ArticleDOI
Kinetics of mace (Myristicae arillus) essential oil extraction using microwave assisted hydrodistillation: Effect of microwave power
TL;DR: In this paper, the main components of the essential oil obtained from hydrodistillation were beta pinene, alpha pinene and myristicin, 4-terpineol, and gamma terpinene.
Journal ArticleDOI
Monoterpenes modulating autophagy: A review study.
TL;DR: The effects of monoterpenes on autophagy and its relationship with therapeutic impacts of monoterspenes are discussed in the present MiniReview.
References
More filters
Journal ArticleDOI
Ginsenoside-Rb1 from Panax ginseng C.A. Meyer Activates Estrogen Receptor-α and -β, Independent of Ligand Binding
TL;DR: The results indicate that the estrogen-like activity of ginsenoside-Rb1 is independent of direct estrogen receptor association, suggesting that it is functionally very similar to 17beta-estradiol.
Journal ArticleDOI
Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways.
TL;DR: In this article, the effects of testosterone and its metabolites DHT and E2 in male 3xTg-AD mice depleted of endogenous sex steroid hormones by gonadectomy (GDX) were evaluated for two indices of AD-like neuropathology, β-amyloid (Aβ) accumulation and tau hyperphosphorylation.
Journal ArticleDOI
Estrogenic Activities of Fatty Acids and a Sterol Isolated from Royal Jelly
Kazumichi Suzuki,Yoichiro Isohama,Hiroe Maruyama,Yayoi Yamada,Yukio Narita,Shozo Ohta,Yoko Araki,Takeshi Miyata,Takeshi Miyata,Satoshi Mishima +9 more
TL;DR: Evidence is provided that four compounds isolated from RJ contribute to the estrogenic effect of RJ, as evidenced by enhanced transcription of a reporter gene containing an estrogen-responsive element.
Journal ArticleDOI
The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes
Rosamaria Lappano,Anna Grazia Recchia,Ernestina Marianna De Francesco,Tommaso Angelone,Maria Carmela Cerra,Didier Picard,Marcello Maggiolini +6 more
TL;DR: It is demonstrated that the estrogen receptor (ER) α mediates gene expression changes and growth responses induced by 25HC in breast and ovarian cancer cells, and the estrogen-like activity of 25HC elicited in the cardiovascular system may play a role against hypoxic environments.
Journal ArticleDOI
Lycopene and other carotenoids inhibit estrogenic activity of 17β-estradiol and genistein in cancer cells
TL;DR: The results suggest that dietary carotenoids inhibit estrogen signaling of both 17β-estradiol and genistein, and attenuate their deleterious effect in hormone-dependent malignancies.