Journal ArticleDOI
Estrogenic terpenes and terpenoids: Pathways, functions and applications.
TLDR
Applications of estrogenic terpenes and terpenoids are categorized into cancer treatment and prevention, cardioprotection, endocrine toxicity/reproductive dysfunction, food/supplement/traditional medicine, immunology/inflammation, menopausal syndromes and neuroprotection, where their benefits are discussed based on their availability, stability and variations.About:
This article is published in European Journal of Pharmacology.The article was published on 2017-11-15. It has received 55 citations till now. The article focuses on the topics: Terpene & Terpenoid.read more
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Antioxidant and antibacterial activity of seven predominant terpenoids
TL;DR: In this article, the efficacy of seven predominant wine terpenoids (i.e. α-pinene, limonene, myrcene, geraniol, linalool, nerol, and terpineol) against foodborne pathogenic bac...
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Nutritional implications of ginger: chemistry, biological activities and signaling pathways.
TL;DR: The molecular mechanisms of estrogen actions induced by ginger constituents and related applications, such as the chemoprevention of cancers, and the improvement of menopausal syndromes, osteoporosis, endometriosis, prostatic hyperplasia, polycystic ovary syndrome and Alzheimer's disease, were summarized by a comprehensive search of references.
Journal ArticleDOI
Ionic Liquid Solutions as a Green Tool for the Extraction and Isolation of Natural Products.
Jiao Xiao,Gang Chen,Ning Li +2 more
TL;DR: The application of ILs to rich the extraction of critical bioactive constituents that were reported possessing multiple therapeutic effects or pharmacological activities, from medicinal plants are described to further reduce the environmental damage caused by large quantity of organic chemical reagents.
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Kinetics of mace (Myristicae arillus) essential oil extraction using microwave assisted hydrodistillation: Effect of microwave power
TL;DR: In this paper, the main components of the essential oil obtained from hydrodistillation were beta pinene, alpha pinene and myristicin, 4-terpineol, and gamma terpinene.
Journal ArticleDOI
Monoterpenes modulating autophagy: A review study.
TL;DR: The effects of monoterpenes on autophagy and its relationship with therapeutic impacts of monoterspenes are discussed in the present MiniReview.
References
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Journal ArticleDOI
Ginsenoside-Rb1 acts as a weak phytoestrogen in MCF-7 human breast cancer cells.
Young Joo Lee,Young Ran Jin,Won Chung Lim,Wan Kyu Park,Jung Yoon Cho,Siyoul Jang,Seung Ki Lee +6 more
TL;DR: The hypothesis that ginsenoside-Rbb1 acts a weak phytoestrogen, presumably by binding and activating the estrogen receptor, is supported.
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Effect of feeding solanidine, solasodine and tomatidine to non-pregnant and pregnant mice.
TL;DR: To obtain evidence for possible mechanisms of the observed in vivo effects, the four glycoalkaloids (alpha-chaconine, alpha-solanine, solasonine and alpha-tomatine) mentioned above and the aglycones solanidine and tomatidine were also evaluated in in vitro assays for estrogenic activity.
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Oleuropein and hydroxytyrosol activate GPER/ GPR30‐dependent pathways leading to apoptosis of ER‐negative SKBR3 breast cancer cells
Adele Chimento,Ivan Casaburi,Camillo Rosano,Paola Avena,Arianna De Luca,Carmela Campana,Emilia Martire,Maria Francesca Santolla,Marcello Maggiolini,Vincenzo Pezzi,Rosa Sirianni +10 more
TL;DR: Showing that OL and HT work as GPER inverse agonists in ER-negative and GPER-positive SKBR3 BC cells provides novel insights into the potential of these two molecules as tools in the therapy of this subtype of BC.
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Attenuation of Aβ25-35-induced parallel autophagic and apoptotic cell death by gypenoside XVII through the estrogen receptor-dependent activation of Nrf2/ARE pathways
Xiangbao Meng,Min Wang,Guibo Sun,Jingxue Ye,Yanhui Zhou,Xi Dong,Tingting Wang,Shan Lu,Xiaobo Sun +8 more
TL;DR: Gypenoside XVII (GP-17) conferred protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, inactivation of GSK-3β and activation of Nrf2/ARE/HO-1 pathways.
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Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage checkpoint.
Kai Zheng,Yan Li,Shaoxiang Wang,Xiao Wang,Chenghui Liao,Xiaopeng Hu,Long Fan,Qiangrong Kang,Yong Zeng,Xuli Wu,Haiqiang Wu,Jian Zhang,Wang Yifei,Zhendan He +13 more
TL;DR: Ginsenoside Ro is a novel autophagy inhibitor and could function as a potent anticancer agent in combination therapy to overcome chemoresistance, according to screened ginsenosides extracted from Panax ginseng.