Exploring AyuGenomics approach for understanding COVID-19 predisposition and progression.
TLDR
The proposed approach of Ayurveda based phenotype screening may offer a way ahead to design customized strategies for management of COVID-19 based on differences in Prakriti, immune response and drug response, however, this needs clinical evaluation of the relation between Prakrati and genetic or phenotypic variants in CO VID-19 prone and resistant populations.About:
This article is published in Journal of Ayurveda and Integrative Medicine.The article was published on 2021-06-17 and is currently open access. It has received 6 citations till now. The article focuses on the topics: Phenotype & Genetic predisposition.read more
Citations
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Integrative approaches for health: Biomedical research, ayurveda, and yoga.
TL;DR: The National Center for Complementary and Alternative Medicine has changed its name, indicating a choice which focuses attention on the question of TCAM on two aspects in particular: The concept of integration and that of health.
Journal ArticleDOI
Effect of breathing intervention in patients with COVID and healthcare workers
Manjari Rain,Goverdhan Dutt Puri,Aashish Bhalla,Pramod Avti,Balachundhar Subramaniam,Vipin Kaushal,Vinod K. Srivastava,Pranay Mahajan,Mini P Singh,Navin Pandey,Pankaj Malhotra,Sonu Goel,Krishan Kumar,Naresh Sachdeva,Kalyan Maity,Prashant Verma,Nishant Dixit,Sheetal Gupta,Priya Mehra,Pooja Nadholta,Radhika Khosla,Shweta Ahuja,Akshay Anand +22 more
TL;DR: The breathing intervention improved exercise capacity in mild to moderate cases of COVID-19 and lowered D-dimer, which is helpful in reducing thrombosis and venous thromboembolism in patients with CO VID-19 besides lowering the chances of vaccine-inducedThrombotic throm bocytopenia in vaccinated individuals.
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An Ayurgenomics Approach: Prakriti-Based Drug Discovery and Development for Personalized Care
Zoufang Huang,Vivek P. Chavda,Rajashri Bezbaruah,Vladimir N. Uversky,S. P.,Aayushi Patel,Zhenhua Chen +6 more
TL;DR: This work tries to understand prakriti’s use in personalized medicine, and how to integrate it with programs for drug development and discovery.
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Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19
TL;DR: In this paper , the authors conducted a review of the main SNPs of these structures that are associated with severity in COVID-19 and identified possible host protection relationships when linked to this infection.
References
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Concept of deha prakriti vis-à-vis human constitution in ayurveda.
Jyoti Tripathi,Singh Rh +1 more
TL;DR: Dehaprakrti is the foremost factor which determines the pattern of susceptibility of an individual to different diseases, their prognosis, course and complications.
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Anguli Parimana in Ayurveda and its association with adiposity and diabetes
TL;DR: Compared with ancient Indian Anguli reference, subjects were proportionately smaller in most of the measurements except fingers and upper arm, and relative smallness of body parts was predictive of increased risk of type 2 diabetes.
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OA07.02. Naturopathic medicine for the prevention of cardiovascular disease: a pragmatic randomized clinical trial.
D Seely,Orest Szczurko,C Kieran,Heidi Fritz,Patricia M. Herman,Ryan Bradley,S Aberdour,C Herrington,Philip Rouchotas,David Lescheid,T Gignac,Bob Bernhardt,Qi Zhou,G. H. Guyatt +13 more
TL;DR: A multi-site pragmatic randomized controlled trial of enhanced usual care (EUC; usual care plus biometric screening) versus EUC plus naturopathic care (eUC +NC), which found incidence of metabolic syndrome and 10-year risk of having a cardiovascular event based on the Framingham algorithm and the Adult Treatment Panel III diagnostic criteria for metabolic syndrome.
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A novel splice site mutation in OTC gene of a female with ornithine transcarbamylase deficiency and her asymptomatic mosaic father.
Shchagina Olga,Semenova Natalia,Bychkov Igor,Chukhrova Alena,Zakharova Ekaterina,Ryzhkova Oksana,Markova Zhanna,Shilova Nadezhda,Poliakov Aleksander +8 more
TL;DR: A case which is caused by a novel c.78-1G>A splice site mutation, which on mRNA level leads to a 1-bp deletion and a frameshift in OTC exon 2 in a young girl, which has been detected in a mosaic state in her asymptomatic father.