Exploring AyuGenomics approach for understanding COVID-19 predisposition and progression.
TLDR
The proposed approach of Ayurveda based phenotype screening may offer a way ahead to design customized strategies for management of COVID-19 based on differences in Prakriti, immune response and drug response, however, this needs clinical evaluation of the relation between Prakrati and genetic or phenotypic variants in CO VID-19 prone and resistant populations.About:
This article is published in Journal of Ayurveda and Integrative Medicine.The article was published on 2021-06-17 and is currently open access. It has received 6 citations till now. The article focuses on the topics: Phenotype & Genetic predisposition.read more
Citations
More filters
Journal Article
Integrative approaches for health: Biomedical research, ayurveda, and yoga.
TL;DR: The National Center for Complementary and Alternative Medicine has changed its name, indicating a choice which focuses attention on the question of TCAM on two aspects in particular: The concept of integration and that of health.
Journal ArticleDOI
Effect of breathing intervention in patients with COVID and healthcare workers
Manjari Rain,Goverdhan Dutt Puri,Aashish Bhalla,Pramod Avti,Balachundhar Subramaniam,Vipin Kaushal,Vinod K. Srivastava,Pranay Mahajan,Mini P Singh,Navin Pandey,Pankaj Malhotra,Sonu Goel,Krishan Kumar,Naresh Sachdeva,Kalyan Maity,Prashant Verma,Nishant Dixit,Sheetal Gupta,Priya Mehra,Pooja Nadholta,Radhika Khosla,Shweta Ahuja,Akshay Anand +22 more
TL;DR: The breathing intervention improved exercise capacity in mild to moderate cases of COVID-19 and lowered D-dimer, which is helpful in reducing thrombosis and venous thromboembolism in patients with CO VID-19 besides lowering the chances of vaccine-inducedThrombotic throm bocytopenia in vaccinated individuals.
Journal ArticleDOI
An Ayurgenomics Approach: Prakriti-Based Drug Discovery and Development for Personalized Care
Zoufang Huang,Vivek P. Chavda,Rajashri Bezbaruah,Vladimir N. Uversky,S. P.,Aayushi Patel,Zhenhua Chen +6 more
TL;DR: This work tries to understand prakriti’s use in personalized medicine, and how to integrate it with programs for drug development and discovery.
Journal ArticleDOI
Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19
TL;DR: In this paper , the authors conducted a review of the main SNPs of these structures that are associated with severity in COVID-19 and identified possible host protection relationships when linked to this infection.
References
More filters
Journal ArticleDOI
Liver injury is associated with severe coronavirus disease 2019 (COVID-19) infection: A systematic review and meta-analysis of retrospective studies.
TL;DR: The incidence of liver injury, as assessed by serum analysis (AST, ALT, total Bilirubin and Albumin levels), seems to be higher in patients with severe COVID‐19 infection.
Journal ArticleDOI
Ayurvedic genomics: establishing a genetic basis for mind-body typologies.
TL;DR: The findings of a Genetic basis for both Ayurvedic and TCM classifications indicate a commonality between Asia's great medical traditions in their diagnostic typologies and a genetic basis for Asian traditional medicine's theory of discrete and discernable groupings of psycho-physiologic differences.
Journal ArticleDOI
SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype.
Naoki Yamamoto,Yasuo Ariumi,Nao Nishida,Rain Yamamoto,Georg Bauer,Takashi Gojobori,Kunitada Shimotohno,Masashi Mizokami +7 more
TL;DR: Analysis of genetic factors associated with SARS-CoV-2 infection with a focus on angiotensin-converting enzyme (ACE)-related genes suggests that the ACE1 II genotype may influence the prevalence and clinical outcome of CO VID-19 and serve as a predictive marker for COVID-19 risk and severity.
Journal ArticleDOI
Traditional Medicine to Modern Pharmacogenomics: Ayurveda Prakriti Type and CYP2C19 Gene Polymorphism Associated with the Metabolic Variability
TL;DR: Interesting correlations between CYP2C19 genotypes and Prakriti with fast and slow metabolism being one of the major distinguishing and differentiating characteristics are observed.
Journal ArticleDOI
The association between frailty and severe disease among COVID-19 patients aged over 60 years in China: a prospective cohort study.
Yao Ma,Lisha Hou,Xiufang Yang,Zhixin Huang,Xue Yang,Na Zhao,Min He,Yixin Shi,Yan Kang,Jirong Yue,Chenkai Wu +10 more
TL;DR: Frailty, assessed by the FRAIL scale, was associated with a higher risk of developing severe disease among older COVID-19 patients and suggested that the use of a clinician friendly assessment of frailty could help in early warning of older patients at high-risk with severe CO VID-19 pneumonia.