Exploring AyuGenomics approach for understanding COVID-19 predisposition and progression.
TLDR
The proposed approach of Ayurveda based phenotype screening may offer a way ahead to design customized strategies for management of COVID-19 based on differences in Prakriti, immune response and drug response, however, this needs clinical evaluation of the relation between Prakrati and genetic or phenotypic variants in CO VID-19 prone and resistant populations.About:
This article is published in Journal of Ayurveda and Integrative Medicine.The article was published on 2021-06-17 and is currently open access. It has received 6 citations till now. The article focuses on the topics: Phenotype & Genetic predisposition.read more
Citations
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Integrative approaches for health: Biomedical research, ayurveda, and yoga.
TL;DR: The National Center for Complementary and Alternative Medicine has changed its name, indicating a choice which focuses attention on the question of TCAM on two aspects in particular: The concept of integration and that of health.
Journal ArticleDOI
Effect of breathing intervention in patients with COVID and healthcare workers
Manjari Rain,Goverdhan Dutt Puri,Aashish Bhalla,Pramod Avti,Balachundhar Subramaniam,Vipin Kaushal,Vinod K. Srivastava,Pranay Mahajan,Mini P Singh,Navin Pandey,Pankaj Malhotra,Sonu Goel,Krishan Kumar,Naresh Sachdeva,Kalyan Maity,Prashant Verma,Nishant Dixit,Sheetal Gupta,Priya Mehra,Pooja Nadholta,Radhika Khosla,Shweta Ahuja,Akshay Anand +22 more
TL;DR: The breathing intervention improved exercise capacity in mild to moderate cases of COVID-19 and lowered D-dimer, which is helpful in reducing thrombosis and venous thromboembolism in patients with CO VID-19 besides lowering the chances of vaccine-inducedThrombotic throm bocytopenia in vaccinated individuals.
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An Ayurgenomics Approach: Prakriti-Based Drug Discovery and Development for Personalized Care
Zoufang Huang,Vivek P. Chavda,Rajashri Bezbaruah,Vladimir N. Uversky,S. P.,Aayushi Patel,Zhenhua Chen +6 more
TL;DR: This work tries to understand prakriti’s use in personalized medicine, and how to integrate it with programs for drug development and discovery.
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Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19
TL;DR: In this paper , the authors conducted a review of the main SNPs of these structures that are associated with severity in COVID-19 and identified possible host protection relationships when linked to this infection.
References
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Journal ArticleDOI
High levels of soluble CD25 in COVID-19 severity suggest a divergence between anti-viral and pro-inflammatory T-cell responses.
Min Xie,Min Xie,Joseph Yunis,Yin Yao,Yin Yao,Jing Shi,Jing Shi,Yang Yang,Yang Yang,Pengcheng Zhou,Pengcheng Zhou,Kaili Liang,Yanmin Wan,Ahmed M. Mehdi,Zhian Chen,Naiqi Wang,Shuyun Xu,Shuyun Xu,Min Zhou,Min Zhou,Muqing Yu,Muqing Yu,Ke Wang,Ke Wang,Yu Tao,Yu Tao,Ying Zhou,Ying Zhou,Xiaochen Li,Xiaochen Li,Xiansheng Liu,Xiansheng Liu,Xiao Yu,Yunbo Wei,Zheng Liu,Jonathan Sprent,Jonathan Sprent,Di Yu +37 more
TL;DR: In this article, a mouse model of acute infection by lymphocytic choriomeningitis virus (LCMV) was applied to dissect the relationship between immunological, virological and pathological features.
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The renin-angiotensin-aldosterone system: Role in pathogenesis and potential therapeutic target in COVID-19.
Cassia L. Braga,Rodrigo P. Silva-Aguiar,Denise Battaglini,Diogo B. Peruchetti,Chiara Robba,Paolo Pelosi,Patricia R. M. Rocco,Celso Caruso-Neves,Pedro L. Silva +8 more
TL;DR: Possible pathways involved in the pathogenesis of COVID‐19 and potential therapeutic targets are highlighted, focusing on the role of the renin–angiotensin–aldosterone system.
Journal Article
Translating Ayurveda's Dosha-Prakriti into objective parameters.
TL;DR: It is interesting, nevertheless, to note that the determinants of Dosha‑Prakriti of a person, as defined in classical Ayurvedic texts, are very similar to those believed to determine the phenotype in modern biology.
Journal Article
Constitutional study of cancer patients - its prognostic and therapeutic scope.
TL;DR: Patients undergoing treatment for Cancer and normal adults are studied for their Prakriti to find out whether there is any difference in the prakriti pattern of Cancer patients when compared with that of normal volunteers.
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Biochemical and Anthropometric Profiles of Different Prakriti (Ayurvedic Constitution) Patients of Non-insulin Dependent Diabetes Mellitus
Hetal Amin,Rohit Sharma +1 more
TL;DR: Dosha dominant Prakriti has an influence on the biochemical and anthropometric parameters of NIDDM patients, which need to be explored in a sample.