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Open AccessJournal ArticleDOI

Fatal dengue hemorrhagic fever in Cuba, 1997

TLDR
The results obtained demonstrate that adults with a primary dengue infection are at risk of developing the severe disease (DHF) if they are infected with a different serotype.
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This article is published in International Journal of Infectious Diseases.The article was published on 1999-03-01 and is currently open access. It has received 152 citations till now. The article focuses on the topics: Dengue fever & Secondary infection.

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Citations
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Dengue: an update

TL;DR: The status of vaccine development is described and it is emphasised that the only alternative that the authors have today to control the disease is through control of its vector Aedes aegypti.
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Dengue Virus Pathogenesis: an Integrated View

TL;DR: A personalized approach to the study of pathogenesis will elucidate the basis of individual risk for development of DHF and DSS as well as identify the genetic and environmental bases for differences in risk forDevelopment of severe disease.
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Dengue viral infections

TL;DR: This review outlines aspects of the epidemiology of d Dengue infections, the dengue virus and its mosquito vector, clinical features and pathogenesis of denge infections, and the management and control of these infections.
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Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of infection

TL;DR: This review is focused on the etiological role of secondary infections (SI) and mechanisms of ADE, which results in an increased number of infected cells and increased viral output per cell at the late illness stage.
References
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Journal ArticleDOI

Dengue and Dengue Hemorrhagic Fever

TL;DR: A review of the changing epidemiology of dengue and hemorrhagic fever by geographic region, the natural history and transmission cycles, clinical diagnosis of both Dengue fever and DVF, serologic and virologic laboratory diagnoses, pathogenesis, surveillance, prevention, and control can be found in this paper.

Dengue and dengue hemorrhagic fever.

TL;DR: A major challenge for public health officials in all tropical areas of the world is to devleop and implement sustainable prevention and control programs that will reverse the trend of emergent dengue hemorrhagic fever.
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Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction.

TL;DR: The accumulated data demonstrated that dengue viruses can be accurately detected and typed from viremic human serum samples.
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Pathogenesis of dengue: challenges to molecular biology

TL;DR: This work has identified a severe syndrome, dengue hemorrhagic fever/dengue shock syndrome, in Southeast Asian children, which recently has also been identified in children infected with the virus in Puerto Rico.
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