Journal ArticleDOI
First and repeat liver resection for primary and recurrent intrahepatic cholangiocarcinoma.
Regis Souche,Pietro Addeo,Elie Oussoultzoglou,Astrid Herrero,Edoardo Rosso,Francis Navarro,Jean Michel Fabre,Philippe Bachellier +7 more
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TLDR
Tumor size more than 5 cm represents an independent risk factor for recurrence after resection of ICC and in case of recurrent ICC, when feasible, is associated with longer overall survival.Abstract:
Background Recurrence after resection of intrahepatic cholangiocarcinoma (ICC) remains common. The present study sought to evaluate risk factors for recurrence and the results of repeat liver resection (RLR) for recurrent ICC. Methods Between 1997 and 2012, clinical data and outcomes of 125 consecutive patients undergoing liver resection for ICC were retrospectively analyzed. Results The rate of R0 resection was 89% (n = 110). Overall median survival was 35 months, and 1-, 3-, and 5-year actuarial survival rates were 80%, 48%, and 28%, respectively. Recurrence occurred in 76 patients (63.5%) and was intrahepatic only for 39 patients (51%). Tumor size greater than 5 cm was identified as an independent risk factor for recurrence ( P ≤ .0001). RLR for recurrent ICC was feasible in 10 patients (25%) with a median survival after recurrence of 25 months (16 to 76). Conclusions Tumor size more than 5 cm represents an independent risk factor for recurrence after resection of ICC. RLR in case of recurrent ICC, when feasible, is associated with longer overall survival.read more
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Hepatectomy or/with Metastatectomy for Recurrent Intrahepatic Cholangiocarcinoma: Of Promise for Selected Patients
Chun-Yi Tsai,Shang-Yu Wang,Kun-Ming Chan,Wei-Chen Lee,Tse-Ching Chen,Ta-Sen Yeh,Yi-Yin Jan,Chun-Nan Yeh +7 more
TL;DR: Liver is the most commonly involved site of recurrent ICC, however, merely intrahepatic recurrence may have a favorable prognosis compared to recurrence involving other sites and Aggressive hepatectomy may provide a survival benefit in selected patients.
Journal ArticleDOI
Advantages of the Laparoscopic Approach for the Initial Operation in Patients who Underwent Repeat Hepatectomy.
H. Gong,Shohei Komatsu,Masahiro Kido,Kenji Fukushima,Takeshi Urade,Shinichi So,Toshihiko Yoshida,Keisuke Arai,Jun Ishida,Yoshihide Nanno,Dai Tsugawa,H. Yanagimoto,Hirochika Toyama,Takumi Fukumoto +13 more
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