Functional bowel disorders and functional abdominal pain.
Reads0
Chats0
TLDR
A committee consensus approach, including criticism from multinational expert reviewers, was used to revise the diagnostic criteria and update diagnosis and treatment recommendations, based on research results.Abstract:
The Rome diagnostic criteria for the functional bowel disorders and functional abdominal pain are used widely in research and practice. A committee consensus approach, including criticism from multinational expert reviewers, was used to revise the diagnostic criteria and update diagnosis and treatment recommendations, based on research results. The terminology was clarified and the diagnostic criteria and management recommendations were revised. A functional bowel disorder (FBD) is diagnosed by characteristic symptoms for at least 12 weeks during the preceding 12 months in the absence of a structural or biochemical explanation. The irritable bowel syndrome, functional abdominal bloating, functional constipation, and functional diarrhea are distinguished by symptom-based diagnostic criteria. Unspecified FBD lacks criteria for the other FBDs. Diagnostic testing is individualized, depending on patient age, primary symptom characteristics, and other clinical and laboratory features. Functional abdominal pain (FAP) is defined as either the FAP syndrome, which requires at least six months of pain with poor relation to gut function and loss of daily activities, or unspecified FAP, which lacks criteria for the FAP syndrome. An organic cause for the pain must be excluded, but aspects of the patient's pain behavior are of primary importance. Treatment of the FBDs relies upon confident diagnosis, explanation, and reassurance. Diet alteration, drug treatment, and psychotherapy may be beneficial, depending on the symptoms and psychological features.read more
Citations
More filters
Journal ArticleDOI
Effect of a second-generation α2δ ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome
Lesley A. Houghton,Catherine Fell,Peter J. Whorwell,Ieuan Jones,David P Sudworth,Jeremy D. Gale +5 more
TL;DR: Pregabalin increased distension sensory thresholds to normal levels in IBS patients with rectal hypersensitivity, suggesting that α2δ ligands are worthy of further investigation in the treatment of visceral pain disorders, including IBS.
Journal ArticleDOI
Ambulatory 24-hour colonic manometry in slow-transit constipation.
TL;DR: Patients with slow-transit constipation exhibited either normal or decreased pressure activity with manometric features suggestive of colonic neuropathy or myopathy as evidenced by absent HAPC or attenuated colonic responses to meals and waking.
Journal ArticleDOI
Irritable bowel syndrome: Diagnosis and pathogenesis
TL;DR: The pathogenesis of IBS seems to be multifactorial, with the following factors playing a central role in the pathogenesis: heritability and genetics, dietary/intestinal microbiota, low-grade inflammation, and disturbances in the neuroendocrine system (NES) of the gut.
Journal ArticleDOI
Validation of the Rome III Criteria for the Diagnosis of Irritable Bowel Syndrome in Secondary Care
Alexander C. Ford,Alexander C. Ford,Premysl Bercik,David Morgan,Carolina Bolino,Maria Ines Pintos–Sanchez,Paul Moayyedi +6 more
TL;DR: Existing diagnostic criteria perform modestly in distinguishing IBS from organic disease and more accurate ways of diagnosing IBS, avoiding the need for investigation, are required.
Journal ArticleDOI
American gastroenterological association medical position statement: Irritable bowel syndrome
TL;DR: The following guidelines were developed as an update to assist the physician in the clinical understanding, diagnosis, and management of patients with irritable bowel syndrome (IBS).
References
More filters
Journal ArticleDOI
U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact.
Douglas A. Drossman,Zhiming Li,E Andruzzi,R D Temple,Nicholas J. Talley,W G Thompson,William E. Whitehead,J Janssens,Peter Funch-Jensen,E Corazziari +9 more
TL;DR: Symptom reporting, except for incontinence, declines with age, and low income is associated with greater symptom reporting, and the rate of work/school absenteeism and physician visits is increased for those having a functional gastrointestinal disorder.
Journal ArticleDOI
Towards positive diagnosis of the irritable bowel
TL;DR: It is concluded that a careful history can increase diagnostic confidence and reduce the amount of investigation in many patients with chronic abdominal pain.
Journal ArticleDOI
Defecation frequency and timing, and stool form in the general population: a prospective study.
TL;DR: It is concluded that conventionally normal bowel function is enjoyed by less than half the population and that, in this aspect of human physiology, younger women are especially disadvantaged.
Journal ArticleDOI
Towards positive diagnosis of the irritable bowel.
S Pearson,P Openshaw +1 more
TL;DR: The prevention of cot deaths is dependent firstly on the recognition by parents of the significance of certain non-specific symptoms and on their decision to involve the primary care services, and secondly on the efficacy of medical intervention at this stage.