scispace - formally typeset
Open AccessJournal ArticleDOI

Functional bowel disorders and functional abdominal pain.

Reads0
Chats0
TLDR
A committee consensus approach, including criticism from multinational expert reviewers, was used to revise the diagnostic criteria and update diagnosis and treatment recommendations, based on research results.
Abstract
The Rome diagnostic criteria for the functional bowel disorders and functional abdominal pain are used widely in research and practice. A committee consensus approach, including criticism from multinational expert reviewers, was used to revise the diagnostic criteria and update diagnosis and treatment recommendations, based on research results. The terminology was clarified and the diagnostic criteria and management recommendations were revised. A functional bowel disorder (FBD) is diagnosed by characteristic symptoms for at least 12 weeks during the preceding 12 months in the absence of a structural or biochemical explanation. The irritable bowel syndrome, functional abdominal bloating, functional constipation, and functional diarrhea are distinguished by symptom-based diagnostic criteria. Unspecified FBD lacks criteria for the other FBDs. Diagnostic testing is individualized, depending on patient age, primary symptom characteristics, and other clinical and laboratory features. Functional abdominal pain (FAP) is defined as either the FAP syndrome, which requires at least six months of pain with poor relation to gut function and loss of daily activities, or unspecified FAP, which lacks criteria for the FAP syndrome. An organic cause for the pain must be excluded, but aspects of the patient's pain behavior are of primary importance. Treatment of the FBDs relies upon confident diagnosis, explanation, and reassurance. Diet alteration, drug treatment, and psychotherapy may be beneficial, depending on the symptoms and psychological features.

read more

Citations
More filters
Journal ArticleDOI

Role of serotonin in the pathophysiology of the irritable bowel syndrome

TL;DR: The 5-HT release from enterochromaffin (EC) cells initiates peristaltic, secretory, vasodilatory, vagal and nociceptive reflexes as mentioned in this paper.
Journal ArticleDOI

Regional Gray Matter Density Changes in Brains of Patients With Irritable Bowel Syndrome

TL;DR: Changes in density of gray matter among regions involved in cognitive/evaluative functions are specifically observed in patients with IBS, whereas changes in other areas of the brain can be explained by levels of anxiety and depression.
Journal ArticleDOI

A model of neural cross-talk and irritation in the pelvis: implications for the overlap of chronic pelvic pain disorders.

TL;DR: In this article, the effects of acute cystitis on distal colonic sensory thresholds to colorectal distention and acute colonic irritation on micturition parameters were assessed.
Journal ArticleDOI

Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity

TL;DR: Elevated colonic lumenal serine protease activity of IBS-D patients evokes a PAR-2-mediated colonic epithelial barrier dysfunction and subsequent allodynia in mice, suggesting a novel organic background in the pathogenesis of Ibs.
Journal ArticleDOI

Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome

TL;DR: Peripheral administration of α-helical CRH improves gastrointestinal motility, visceral perception, and negative mood in response to gut stimulation, without affecting the hypothalamo-pituitary-adrenal axis in IBS patients.
References
More filters
Journal ArticleDOI

U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact.

TL;DR: Symptom reporting, except for incontinence, declines with age, and low income is associated with greater symptom reporting, and the rate of work/school absenteeism and physician visits is increased for those having a functional gastrointestinal disorder.
Journal ArticleDOI

Towards positive diagnosis of the irritable bowel

TL;DR: It is concluded that a careful history can increase diagnostic confidence and reduce the amount of investigation in many patients with chronic abdominal pain.
Journal ArticleDOI

Defecation frequency and timing, and stool form in the general population: a prospective study.

TL;DR: It is concluded that conventionally normal bowel function is enjoyed by less than half the population and that, in this aspect of human physiology, younger women are especially disadvantaged.
Journal ArticleDOI

Towards positive diagnosis of the irritable bowel.

S Pearson, +1 more
- 25 Nov 1978 - 
TL;DR: The prevention of cot deaths is dependent firstly on the recognition by parents of the significance of certain non-specific symptoms and on their decision to involve the primary care services, and secondly on the efficacy of medical intervention at this stage.
Related Papers (5)