Functional mechanisms of probiotics
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This article is published in The Journal of Microbiology, Biotechnology and Food Sciences.The article was published on 2015-02-01 and is currently open access. It has received 65 citations till now.read more
Citations
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Journal ArticleDOI
Bifidobacteria-Insight into clinical outcomes and mechanisms of its probiotic action.
Amrita Sarkar,Santanu Mandal +1 more
TL;DR: Sc scope for developing advanced structural therapeutic strategy which might be pivotal in replacing intact cell probiotics therapy is highlighted, which could help in developing customised formulations against targeted pathogens.
Journal ArticleDOI
A review : the fate of bacteriocins in the human gastro-intestinal tract : do they cross the gut–blood barrier?
TL;DR: The stability of bacteriocins in the GIT, their effect on gut epithelial cells, and their ability to cross epithelial barriers are discussed, in the light of recent papers advocating the use of bacter iocins as possible alternatives to, or used in combination with, antibiotics.
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Saccharomyces boulardii: What Makes It Tick as Successful Probiotic?
TL;DR: The main genetic divergencies between S. boulardii and S. cerevisiae are reviewed as a strategy to uncover the ability to adapt to the host physiological conditions by the probiotic.
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Beneficial roles of probiotics on the modulation of gut microbiota and immune response in pigs.
Donghyun Shin,Sung Yong Chang,Paul Bogere,Kyeong-Hye Won,Jae-Young Choi,Yeon-jae Choi,Hak Kyo Lee,Jin Hur,Byung-Yong Park,Younghoon Kim,Jaeyoung Heo +10 more
TL;DR: The data suggest that L. plantarum JDFM LP11 increases the diversity and richness in the microbial community, and attenuates the ileal immune gene expression towards gut inflammation, promoting intestinal development in weaned piglets.
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Probiotics at War Against Viruses: What Is Missing From the Picture?
Santosh Kumar Tiwari,Leon M. T. Dicks,Igor V. Popov,Alena Karaseva,Alexey Ermakov,Alexander Suvorov,John R. Tagg,Richard Weeks,Michael L. Chikindas +8 more
TL;DR: The present review focusses attention on viruses capable of co-infecting humans and other animals and specifically explores the potential of probiotic bacteria and their metabolites to intervene with the process of virus infection.
References
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Journal ArticleDOI
CD40 and CD154 in cell-mediated immunity.
TL;DR: The role of the CD40-CD154 system is focused on in the regulation of many newly discovered functions important in inflammation and cell-mediated immunity.
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Probiotics, prebiotics, and synbiotics—approaching a definition
TL;DR: The probiotic concept is confined to effects exerted by viable microorganisms but is applicable independent of the site of action and route of administration, and may include sites such as the oral cavity, the intestine, the vagina, and the skin.
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Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
J. Rodrigo Mora,Makoto Iwata,Bertus Eksteen,Si-Young Song,Tobias Junt,Balimkiz Senman,Kevin L. Otipoby,Aya Yokota,Hajime Takeuchi,Paola Ricciardi-Castagnoli,Klaus Rajewsky,David H. Adams,Ulrich H. von Andrian +12 more
TL;DR: It is shown that dendritic cells from GALT induce T cell–independent expression of IgA and gut-homing receptors on B cells, which shape mucosal immunity by modulating B cell migration and effector activity through synergistically acting mediators.
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Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens
TL;DR: This Review highlights the documented signalling interactions of the surface molecules of probiotic bacteria (such as long surface appendages, polysaccharides and lipoteichoic acids) with PRRs with respect to host pattern recognition receptors of the gastrointestinal mucosa.
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Probiotic Mechanisms of Action
Miriam Bermudez-Brito,Julio Plaza-Díaz,Sergio Muñoz-Quezada,Carolina Gomez-Llorente,Angel Gil +4 more
TL;DR: Probiotics modes of action focusing on how gut microbes influence the host are explored, with a clear understanding of these mechanisms allowing for appropriate probiotic strain selection for specific applications and may uncover novel probiotic functions.