Journal ArticleDOI
Functional Micro-/Nanomaterials for Multiplexed Biodetection.
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TLDR
In this article, the role of micro-and nanomaterials in the improvement of multiplexed biodetection strategies is discussed and analyzed, and available solutions made possible by designing and controlling the properties of micro and nano-materials are introduced.Abstract:
When analyzing biological phenomena and processes, multiplexed biodetection has many advantages over single-factor biodetection and is highly relevant to both human health issues and advancements in the life sciences. However, many key problems with current multiplexed biodetection strategies remain unresolved. Herein, the main issues are analyzed and summarized: 1) generating sufficient signal to label targets, 2) improving the signal-to-noise ratio to ensure total detection sensitivity, and 3) simplifying the detection process to reduce the time and labor costs of multiple target detection. Then, available solutions made possible by designing and controlling the properties of micro- and nanomaterials are introduced. The aim is to emphasize the role that micro-/nanomaterials can play in the improvement of multiplexed biodetection strategies. Through analyzing existing problems, introducing state-of-the-art developments regarding relevant materials, and discussing future directions of the field, it is hopeful to help promote necessary developments in multiplexed biodetection and associated scientific research.read more
Citations
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Designing Next Generation of Persistent Luminescence: Recent Advances in Uniform Persistent Luminescence Nanoparticles
TL;DR: In this paper , the evolution of uniform persistent luminescence nanoparticles, from their bulk phosphor counterparts, to the recent "bottom-up" synthesis of uniform PLNPs is summarized.
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“Ready-to-use” immunosensor for the detection of small molecules with fast readout
TL;DR: In this paper , a homogeneous competitive immunosensor with an assay time of 10 min that is based exclusively on recombinant reagents was presented. But the authors did not consider the effects of the spacer between the peptidomimetic and LgN, and the copy number of peptidimetics, generating 24 combinations that allowed to conclude on their respective roles.
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Multiple detection of 15 triazine herbicides by gold nanoparticle based-paper sensor
TL;DR: In this paper , an effective immunochromatographic strip test that can simultaneously detect 15 different triazines in grain samples (including ametryn, cyprazine, atraton, prometon, prometryn and simetone) was developed.
Journal ArticleDOI
DNA Supramolecular Assembly on Micro/Nanointerfaces for Bioanalysis.
TL;DR: The work on DNA supramolecular assembly on micro/nanointerfaces for bioanalysis will be a typical paradigm for the construction of more bioanalytical materials, which the authors hope will facilitate the development of precision medicine.
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Dye-sensitized lanthanide containing nanoparticles for luminescence based applications.
TL;DR: In this paper , the spectral properties of lanthanides both in complexes and in nanoparticles (NPs) are discussed and a comparison of the advantages and drawbacks of the three types of NPs is provided as well as a conclusion about the remaining challenges both in the design of brighter NPs and in the luminescence based applications.
References
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Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
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Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
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