Journal ArticleDOI
Gold nanoparticles in delivery applications
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Gold nanoparticles provide non-toxic carriers for drug and gene delivery applications and their interaction with thiols is an effective and selective means of controlled intracellular release.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-08-17. It has received 2383 citations till now. The article focuses on the topics: Colloidal gold & Drug delivery.read more
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The golden age: gold nanoparticles for biomedicine
TL;DR: It is argued that gold nanotechnology-enabled biomedicine is not simply an act of 'gilding the (nanomedicinal) lily', but that a new 'Golden Age' of biomedical nanotechnology is truly upon us.
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Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity
Elodie Boisselier,Didier Astruc +1 more
TL;DR: This critical review provides an overall survey of the basic concepts and up-to-date literature results concerning the very promising use of gold nanoparticles (AuNPs) for medicinal applications.
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Cancer Nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
TL;DR: The fundamental concepts of enhanced permeability and retention effect (EPR) are revisited and the mechanisms proposed to enhance preferential "retention" in the tumor, whether using active targeting of nanoparticles, binding of drugs to their tumoral targets or the presence of tumor associated macrophages are explored.
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Functional Nanomaterials for Phototherapies of Cancer
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Biological applications of gold nanoparticles
TL;DR: This critical review gives a short overview of the widespread use of gold nanoparticles in biology, identifying four classes of applications in which gold nanoparticle have been used so far: labelling, delivering, heating, and sensing.
References
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Journal ArticleDOI
A study of the nucleation and growth processes in the synthesis of colloidal gold
TL;DR: In this paper, a preliminary survey with the electron microscope of various preparations of colloidal gold, a study was made of the process of nucleation and growth in gold colloids, and it was shown that nucleating agents may be identified with reducing agents which form a mixed polymer with chlorauric ion before the reduction to the nucleus takes place.
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Synthesis of thiol-derivatised gold nanoparticles in a two-phase liquid-liquid system
TL;DR: Using two-phase reduction of AuCl4 by sodium borohydride in the presence of an alkanethiol, solutions of 1-3 nm gold particles bearing a surface coating of thiol have been prepared and characterised; this novel material can be handled as a simple chemical compound as mentioned in this paper.
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Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells.
TL;DR: The intracellular uptake of different sized and shaped colloidal gold nanoparticles is investigated and it is shown that kinetics and saturation concentrations are highly dependent upon the physical dimensions of the nanoparticles.
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Nanostructures in Biodiagnostics
Nathaniel L. Rosi,Chad A. Mirkin +1 more
TL;DR: Nathaniel L. Rosi focuses on the rational assembly of DNA-modified nanostructures into larger-scale materials and their roles in biodiagnostic screening for nucleic acids.