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Hemangioendotelioma epitelióide do pulmão - Raridade, dificuldades diagnósticas e terapêutica Pulmonary epithelioid hemangioendothelioma - Rarity, diagnosis and treatment difficulties
Telma Lopes,Susana Clemente,Amélia Feliciano,Isabel Lourenço,Agostinho Costa,Joaquim Gil Duarte +5 more
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Abstract:
Resumo Os autores apresentam um caso de hemangioendotelioma epitelioide (HEE) primario do pulmao num doente de 51 anos, sexo masculino, que iniciou queixas de tosse seca, seguida de sintomas constitucionais e dispneia. Apos realizacao de alguns exames complementares de diagnostico, que incluiram biopsia cirurgica, foi considerada a hipotese de tuberculose pulmonar e iniciou antibacilares, que manteve durante tres semanas. Por agravamento clinico e imagiologico, foi feita revisao do caso e estudo imunoistoquimicoread more
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Pazopanib for metastatic pulmonary epithelioid hemangioendothelioma—a suitable treatment option: case report and review of anti-angiogenic treatment options
TL;DR: This case is the first to report objective, long-lasting response to pazopanib in metastatic pulmonary epithelioid hemangioendothelioma, a rare vascular tumor of borderline or low-grade malignancy.
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Treatment of pulmonary epithelioid hemangioendothelioma with combination chemotherapy: Report of three cases and review of the literature
TL;DR: It is indicated that patients with PEH demonstrated a good partial response to chemotherapy with carboplatin, paclitaxel, bevacizumab, thalidomide and α-interferon, which may hold therapeutic potential for the treatment of this rare disease.
Journal ArticleDOI
Pleural epithelioid hemangioendothelioma in an elderly patient. A case report and review of the literature.
Diego Marquez-Medina,Juan Carlos Samamé-Pérez-Vargas,Noemi Tuset-DerAbrain,Angeles Montero-Fernández,Teresa Taberner-Bonastre,José M. Porcel +5 more
TL;DR: The case of an 85 years old male patient diagnosed of pleural epithelioid hemangioendothelioma, taking advantage to review exhaustively literature and therapy for the disease is reported.
Journal ArticleDOI
Primary lung neoplasms presenting as multiple synchronous lung nodules
TL;DR: Several rare primary lung neoplasms that originate from epithelial, mesenchymal and lymphoid tissues of the lung present as multiple synchronous indeterminate lung nodules on chest CT merit increased awareness among radiologists, pathologists and pulmonologists, as well as a multidisciplinary team approach.
Journal ArticleDOI
Epithelioid hemangioendothelioma presenting as malignant biliary stricture.
TL;DR: A 69-year-old Caucasian man with a history of hypertension, diabetes mellitus, and metastatic pulmonary epithelioid hemangioendothelioma presented with jaundice and pruritus and was admitted to the hospital with Clostridium difficile colitis and acute hypoxic respiratory failure secondary to healthcare-associated pneumonia, and expired a few days after admission.
References
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Pulmonary epithelioid haemangioendothelioma in 21 patients, including three with partial spontaneous regression
Masanori Kitaichi,Sonoko Nagai,Koichi Nishimura,Harumi Itoh,Asamoto H,Takateru Izumi,DH Dail +6 more
TL;DR: This investigation studied the general conditions and prognostic factors of pulmonary epithelioid haemangioendothelioma, which is a rare disease, and three patients demonstrated partial spontaneous regression, and adverse prognostic features were identified.
Journal ArticleDOI
Aggressive form of pleural epithelioid haemangioendothelioma : complete response after chemotherapy
TL;DR: This study describes a case of bilateral pleural epithelioid haemangioendothelioma that extended to the peritoneum that was confirmed by both conventional examination and immunohistochemistry and a complete response was obtained.
Journal ArticleDOI
Successful treatment of primary pulmonary angiosarcoma.
Keisuke Kojima,Isamu Okamoto,Sunao Ushijima,Takeshi Yoshinaga,Mitsuhiko Kitaoka,Moritaka Suga,Yutaka Sasaki +6 more
TL;DR: The case of a patient with primary pulmonary angiosarcoma who responded to a combination of radiotherapy and immunotherapy with recombinant interleukin-2 is reported, and the patient remains well without signs of recurrence 1 year after initial presentation.
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Malignant vascular tumours of the pleura in “asbestos” workers and endothelial differentiation in malignant mesothelioma
Richard Attanoos,S K Suvarna,E Rhead,M Stephens,T J Locke,M N Sheppard,Frederick D. Pooley,Allen R. Gibbs +7 more
TL;DR: Endothelial differentiation does not appear to occur in mesothelioma and therefore should be clearly separated from it, and no definite association between pleural epithelioid haemangioendothelIoma and exposure to asbestos can be made from this small series of cases.