Journal ArticleDOI
Hemizona assay and teratozoospermia: increasing sperm insemination concentrations to enhance zona pellucida binding *
Daniel R. Franken,Thinus F. Kruger,Roelof Menkveld,Sergio Oehninger,Charles C. Coddington,Gary D. Hodgen +5 more
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TLDR
In this paper, the authors evaluated the zona-binding capacity of patients with abnormal sperm morphology, using standard hemizona assay (HZA) conditions and increasing sperm insemination concentration during the assay and determined the minimum concentration of motile sperm from fertile controls necessary to validate HZA results, using sperm from teratozoospermic patients versus proven fertile controls.About:
This article is published in Fertility and Sterility.The article was published on 1990-09-01. It has received 54 citations till now. The article focuses on the topics: Abnormal sperm morphology & Sperm.read more
Citations
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Journal ArticleDOI
Baboon spermatozoa-zona pellucida binding assay.
TL;DR: This system allows for the short-term maintenance of baboon sperm in a semiquiescent state until stimulation with the activators, caffeine and dbcAMP, and provides a novel approach to delineating a contraceptive regimen's or agent's impact on specific cellular events occurring in the male gamete during fertilization.
Journal ArticleDOI
Sperm morphology and DNA fragmentation after zona pellucida selection
Rumiana Ganeva,Dimitar Parvanov,Denitsa Velikova,Magdalena Vasileva,Kristina Nikolova,Georgi Stamenov +5 more
TL;DR: It is demonstrated that sperm selection by additional zona-adhesion technique yields a significantly higher percentage of spermatozoa with normal morphology as well as a significantly decreased level of DNA fragmentation when compared to the native semen and the swim-up-only prepared samples.
Journal ArticleDOI
Development of a predictive model for optimal zona pellucida binding using insemination volume and sperm concentration
Kemal Ozgur,Kemal Ozgur,Kemal Ozgur,Daniel R. Franken,Daniel R. Franken,Daniel R. Franken,Khalied Kaskar,Khalied Kaskar,Khalied Kaskar,Carl J. Lombard,Carl J. Lombard,Carl J. Lombard,Thinus F. Kruger,Thinus F. Kruger,Thinus F. Kruger +14 more
TL;DR: In this paper, a predictive model was developed under hemizona assay (HZA) conditions for human spermatozoa concentrations and insemination volume for optimum zona pellucida (ZP) binding.
Dissertation
Acrosome size and kinematics of human spermatozoa
TL;DR: An analysis of the morphometric and kinematic qualities of spermatozoa populations that are subjected to swim-up selection is presented and the relationship of these morphometrical and k Cinematic qualities is investigated.
Journal ArticleDOI
The influence of sperm/zona pellucida collision rates on zona binding
K. Özgür,Daniel R. Franken +1 more
TL;DR: The collision rate of a sperm population with the human zona pellucida is calculated using a mathematical hypothesis and the calculated collision rate can be used as a guideline to calculate the optimum insemination concentration to ensure the maximum collision rates with the oocyte.
References
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Journal ArticleDOI
Sperm morphologic features as a prognostic factor in in vitro fertilization.
Thinus F. Kruger,Roelof Menkveld,F. S. H. Stander,Carl Lombard,Jacobus P. Van der Merwe,Johannes A. van Zyl,Karen Smith +6 more
TL;DR: In this article, the authors conducted a prospective study in women with bilateral tubal damage to determine whether there is a prognostic value in the percentage normal sperm morphologic features in a human in vitro fertilization (IVF) program.
Journal ArticleDOI
Predictive value of abnormal sperm morphology in in vitro fertilization
Thinus F. Kruger,Anibal A. Acosta,Anibal A. Acosta,K.F. Simmons,K.F. Simmons,R.J. Swanson,R.J. Swanson,J.F. Matta,J.F. Matta,Sergio Oehninger,Sergio Oehninger +10 more
TL;DR: By evaluating sperm morphology with the proposed strict criteria, its predictive value in in vitro fertilization is enhanced.
Journal ArticleDOI
The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential * † ‡
Lani J. Burkman,Charles C. Coddington,Daniel R. Franken,Thinus F. Kruger,Zev Rosenwaks,Gary D. Hodgen +5 more
TL;DR: Sperm from fertile men exhibited significantly higher binding capacity to hemizonae compared with sperm from men who had fertilization failure during in vitro fertilization (IVF) treatment, demonstrating that the HZA may be a useful diagnostic tool in male infertility evaluations.
Journal ArticleDOI
Corrective measures and pregnancy outcome in in vitro fertilization in patients with severe sperm morphology abnormalities
Sergio Oehninger,Anibal A. Acosta,Mahmood Morshedi,Lucinda L. Veeck,R. James Swanson,Kathryn F. Simmons,Zev Rosenwaks +6 more
TL;DR: It is concluded that patients with severe sperm head abnormalities have a lower ability to establish successful pregnancies, even though fertilization may be achieved.
Journal ArticleDOI
Sperm/egg interaction: The specificity of human spermatozoa
TL;DR: The demonstration of a compatibility between the gametes of man and gibbon, not shared with cercopithecids, constitutes further evidence for inclusion of the Hylobatidae within the Hominoidea.