Journal ArticleDOI
Hemoglobin Rush [β101 (G3) Glutamine]: A New Unstable Hemoglobin Causing Mild Hemolytic Anemia
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TLDR
A mild hemolytic anemia in a 43-yr-old black woman was attributed to the presence of an abnormal hemoglobin (Hb Rush) which migrated cathodically to Hb A at pH 8.0, and Hb Rush is heat unstable.About:
This article is published in Blood.The article was published on 1974-02-01. It has received 37 citations till now. The article focuses on the topics: Abnormal hemoglobin & Hemolytic anemia.read more
Citations
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Isolation and characterization of a new hemoglobin derivative cross-linked between the alpha chains (lysine 99 alpha 1----lysine 99 alpha 2).
Ranjit Chatterjee,E. V. Welty,Roxanne Y. Walder,S. L. Pruitt,P. H. Rogers,Arthur Arnone,Joseph A. Walder +6 more
TL;DR: Analysis of the structure suggests that in the cross-linked derivative Glu-101 beta, which is in close proximity to Lys-99 alpha in oxyhemoglobin, becomes an acid Bohr group.
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International Hemoglobin Information Center Variant List
TL;DR: The International Hemoglobin Information Center (IHIC) variant list as discussed by the authors is the most comprehensive list of variants of hemoglobin available in the literature. But it does not specify the variants of each variant.
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A compilation of amino acid analyses of proteins. II
TL;DR: The amino acid analyses of 186 proteins are given as residues per 1000 residues and carbohydrate composition, content of uncomon amino acids, and sources of all proteins are presented.
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The structure of hemoglobin Indianapolis [beta112(G14) arginine]. An unstable variant detectable only by isotopic labeling.
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Molecular analysis of the beta-thalassemia phenotype associated with inheritance of hemoglobin E (alpha 2 beta2(26)Glu leads to Lys).
Edward J. Benz,B W Berman,Barry L. Tonkonow,Elaine Coupal,Thomas D. Coates,Laurence A. Boxer,A Altman,J G Adams rd +7 more
TL;DR: The beta-thalassemia phenotype associated with inheritance of Hb E is thus determined at the level of beta-globin mRNA metabolism, and analysis of globin mRNA by cell-free translation and molecular hybridization confirmed that the unexpectedly low levels of betaE-globar synthesis were associated with comparable reduction in the levels of BetaE- globin mRNA.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Abnormal human haemoglobins. Separation and characterization of the alpha and beta chains by chromatography, and the determination of two new variants, hb Chesapeak and hb J (Bangkok).
TL;DR: In this article, a method for the separation of the α and β chains of human haemoglobin by chromatography on carboxymethyl-cellulose in 8 M -urea has been described.
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Three-dimensional Fourier Synthesis of Horse Oxyhaemoglobin at 2.8 Å Resolution: The Atomic Model
TL;DR: The structure of the contacts between unlike subunits suggests that the tetramer, rather than the αβ dimer, is the functional unit of haemoglobin.
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Phenanthrenequinone as an analytical reagent for arginine and other monosubstituted guanidines
Shigeki Yamada,Harvey A. Itano +1 more
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Studies on the oxygen and carbon monoxide equilibria of human myoglobin
A. Rossi-Fanelli,Eraldo Antonini +1 more
TL;DR: A new spectrophotometric method of determining the oxygendissociation curves of Mb (and Hb) has been developed and the oxygen equilibrium of human crystallized Mb has been studied by this method.