Journal ArticleDOI
Hyperchloremia after noncardiac surgery is independently associated with increased morbidity and mortality: a propensity-matched cohort study.
Stuart A. McCluskey,Keyvan Karkouti,Duminda N. Wijeysundera,Leonid Minkovich,Gordon Tait,W. Scott Beattie +5 more
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TLDR
A retrospective cohort trial demonstrates an association between hyperchloremia and poor postoperative outcome and additional studies are required to demonstrate a causal relationship between these variables.Abstract:
BACKGROUND:The use of normal saline is associated with hyperchloremic metabolic acidosis. In this study, we sought to determine the incidence of acute postoperative hyperchloremia (serum chloride >110 mEq/L) and whether this electrolyte disturbance is associated with an increase in length of hospitaread more
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Guidelines for perioperative care in elective colonic surgery: Enhanced recovery after surgery (ERAS®) society recommendations
Ulf Gustafsson,Michael J. Scott,Michael J. Scott,W. Schwenk,Nicolas Demartines,Didier Roulin,Nader K. Francis,Clare McNaught,John MacFie,A. S. Liberman,Mattias Soop,Andrew G. Hill,Robin H. Kennedy,Dileep N. Lobo,Kenneth C. H. Fearon,Olle Ljungqvist,Olle Ljungqvist +16 more
TL;DR: Based on the evidence available for each item of the multimodal perioperative care pathway, the Enhanced Recovery After Surgery (ERAS) Society, International Association for Surgical Metabolism and Nutrition (IASMEN) and European Society for Clinical Nutrition and Metabolicism (ESPEN) present a comprehensive evidence-based consensus review of peri operative care for colonic surgery.
Journal ArticleDOI
Intravenous Fluids and Acute Kidney Injury
TL;DR: In the setting of established acute kidney injury, fluid management can be challenging, and impaired capacity of urine output and urine concentration and dilution should be taken into consideration when designing fluid therapy.
Journal ArticleDOI
Consensus Guidelines for Enhanced Recovery After Gastrectomy: Enhanced Recovery After Surgery (ERAS®) Society Recommendations
Kim Erlend Mortensen,Magnus Nilsson,Karem Slim,Markus Schäfer,Christophe Mariette,Marco Braga,Franco Carli,Nicolas Demartines,S. M. Griffin,Kristoffer Lassen +9 more
TL;DR: Application of evidence‐based perioperative care protocols reduces complication rates, accelerates recovery and shortens hospital stay.
Journal ArticleDOI
Association of intraoperative hypotension with acute kidney injury after elective noncardiac surgery.
TL;DR: Postoperative AKI is associated with sustained intraoperative periods of MAP less than 55 and less than 60 mmHg, which provides an impetus for clinical trials to determine whether interventions that promptly treat IOH and are tailored to individual patient physiology could help reduce the risk of AKI.
Journal ArticleDOI
Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice
Aarne Feldheiser,O. Aziz,Gabriele Baldini,B Cox,Kch C. H. Fearon,Ls S. Feldman,Tj J. Gan,Rh H. Kennedy,Olle Ljungqvist,Dn N. Lobo,Timothy E. Miller,Ff F. Radtke,T. Ruiz Garces,T. Schricker,Mj J. Scott,Jk K. Thacker,Lm M. Ytrebø,Franco Carli +17 more
TL;DR: Clinical considerations and recommendations for anaesthetic practice in patients undergoing gastrointestinal surgery with an Enhanced Recovery after Surgery (ERAS) programme are proposed.
References
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Journal ArticleDOI
Prediction of Creatinine Clearance from Serum Creatinine
Donald W. Cockcroft,M H Gault +1 more
TL;DR: A formula has been developed to predict Creatinine clearance from serum creatinine (Scr) in adult males: Ccr = (140 – age) (wt kg)/72 × Scr (mg/100ml) (15% less i).
Journal ArticleDOI
Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data.
Hude Quan,Vijaya Sundararajan,Patricia Halfon,Andrew Fong,Bernard Burnand,Jean-Christophe Luthi,L. Duncan Saunders,Cynthia A. Beck,Thomas E Feasby,William A. Ghali +9 more
TL;DR: A multistep process to develop ICD-10 coding algorithms to define Charlson and Elixhauser comorbidities in administrative data and assess the performance of the resulting algorithms found these newly developed algorithms produce similar estimates ofComorbidity prevalence in administrativeData, and may outperform existing I CD-9-CM coding algorithms.
Journal ArticleDOI
An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies
TL;DR: The propensity score is a balancing score: conditional on the propensity score, the distribution of observed baseline covariates will be similar between treated and untreated subjects, and different causal average treatment effects and their relationship with propensity score analyses are described.
Journal Article
The environment and disease: association or causation?
TL;DR: This paper contrasts Bradford Hill’s approach with a currently fashionable framework for reasoning about statistical associations – the Common Task Framework – and suggests why following Bradford Hill, 50+ years on, is still extraordinarily reasonable.
Journal ArticleDOI
Rapid saline infusion produces hyperchloremic acidosis in patients undergoing gynecologic surgery
TL;DR: Infusion of 0.9% saline, but not lactated Ringer's solution, caused a metabolic acidosis with hyperchloremia and a concomitant decrease in the strong ion difference and the amount of weak plasma acid.
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