Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool
TLDR
This scoring algorithm may be helpful in identifying critically ill patients most likely to benefit from aggressive nutrition therapy in the intensive care unit (ICU), and based on the statistical significance in the multivariable model, the final score used all candidate variables except BMI.Abstract:
To develop a scoring method for quantifying nutrition risk in the intensive care unit (ICU). A prospective, observational study of patients expected to stay > 24 hours. We collected data for key variables considered for inclusion in the score which included: age, baseline APACHE II, baseline SOFA score, number of comorbidities, days from hospital admission to ICU admission, Body Mass Index (BMI) < 20, estimated % oral intake in the week prior, weight loss in the last 3 months and serum interleukin-6 (IL-6), procalcitonin (PCT), and C-reactive protein (CRP) levels. Approximate quintiles of each variable were assigned points based on the strength of their association with 28 day mortality. A total of 597 patients were enrolled in this study. Based on the statistical significance in the multivariable model, the final score used all candidate variables except BMI, CRP, PCT, estimated percentage oral intake and weight loss. As the score increased, so did mortality rate and duration of mechanical ventilation. Logistic regression demonstrated that nutritional adequacy modifies the association between the score and 28 day mortality (p = 0.01). This scoring algorithm may be helpful in identifying critically ill patients most likely to benefit from aggressive nutrition therapy.read more
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Journal ArticleDOI
Advances in nutrition for the surgical patient.
D. Dante Yeh,Matthew J. Martin,Joseph V. Sakran,Karien Meier,April E. Mendoza,April A. Grant,Jonathan Parks,Saskya Byerly,Eugenia Ester Lee,William I McKinley,Stephen A. McClave,Keith R. Miller,John E. Mazuski,Beth Taylor,Casey M. Luckhurst,Peter J. Fagenholz +15 more
Journal ArticleDOI
Association between early nutrition support and 28-day mortality in critically ill patients: the FRANS prospective nutrition cohort study
Emmanuel Pardo,Thomas Lescot,Jean-Charles Preiser,Pablo Massanet,A. Pons,Samir Jaber,Vincent Fraipont,Eric Levesque,Carole Ichai,Laurent Petit,Fabienne Tamion,Garry Taverny,Priscilla Boizeau,Corinne Alberti,Jean-Michel Constantin,Marie-Pierre Bonnet,Désiré Samba,Jean Denis Moyer,Philippe Montravers,Nicolas Mongardon,Arnaud Meffert,Audrey De Jong,Fouad Belafia,Jérôme Morel,Karim Asehnoune,Pierre Joachim Mahe,Alain D’hondt,N. Paquot,Marc Leone,Michel Kaidomar,Ludovic Grech,E Gouteix,Elise Barsam,Jacques Duranteau,Orianne Martinez +34 more
TL;DR: Early nutrition was more frequently prescribed in the presence of multiple organ failure and less frequently in overweight and obese patients in the ICU and was associated with increased mortality at day 28 (D28) as discussed by the authors .
Journal ArticleDOI
The Relationship between Serum Concentrations of Pro- and Anti-Inflammatory Cytokines and Nutritional Status in Patients with Traumatic Head Injury in the Intensive Care Unit
Mohammed Ibrahim Mohialdeen Gubari,Abdolreza Norouzy,Mostafa Hosseini,Fadhil Ahmed Mohialdeen,Mohammad Javad Hosseinzadeh-Attar,Mohammad Javad Hosseinzadeh-Attar +5 more
TL;DR: THI patients who had high serum levels of studied cytokines were more prone to develop a reduction of nutritional status in terms of BMI, FBM, LBM MAUAC and APM over the course of time from patient admission until day 13 of ICU admission.
Journal ArticleDOI
Impact of Enteral Feeding on Vasoactive Support in Septic Shock: A Retrospective Observational Study.
Matthew Ewy,Masooma Aqeel,Michelle Kozeniecki,Kadam Patel,Anjishnu Banerjee,Daren K. Heyland,Jayshil J. Patel +6 more
TL;DR: The median vasopressor dose did not increase by ≥50% during the first 24 hours of EN, which suggests early EN delivered during septic shock is not associated with worsening hemodynamic instability.
Journal ArticleDOI
Association Between Enteral Feeding, Weight Status, and Mortality in a Medical Intensive Care Unit
Michael T. Vest,Paul Kolm,James M. Bowen,Jillian Trabulsi,Shannon L. Lennon,Mary Shapero,Patty McGraw,James Halbert,Claudine Jurkovitz +8 more
TL;DR: The finding of a positive association between an order for enteral feeding and survival supportsEnteral feeding of patients in medical intensive care units and the beneficial effect of enteral feed appears to apply to patients regardless of body mass index.
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