Impact of overweight and underweight on assisted reproduction treatment
Peter Fedorcsak,Per Olav Dale,Ritsa Storeng,Gudvor Ertzeid,Sverre Bjercke,Nan B. Oldereid,Anne Katerine Omland,Thomas Åbyholm,Tom Tanbo +8 more
TLDR
Obesity is associated with lower chances for live birth after IVF and ICSI and with an impaired response to ovarian stimulation and with a increased risk of early pregnancy loss occurring before 6 weeks gestation.Abstract:
RESULTS: The cumulative live birth rate within three treatment cycles was 41.4% [95% confidence interval (CI) 32.1– 50.7] in obese women with BMI $30 kg/m 2 and 50.3 (95% CI 47.0–53.7) in normal weight women with BMI 18.5– 24.9 kg/m 2 . Obesity was associated with an increased risk of early pregnancy loss occurring before 6 weeks gestation. Positive correlation between BMI and gonadotrophin requirement during stimulation and negative correlation between BMI and number of collected oocytes were observed. Underweight (BMI < 18.5 kg/m 2 ) was not related to an impaired outcome of IVF or ICSI. CONCLUSIONS: Obesity is associated with lower chances for live birth after IVF and ICSI and with an impaired response to ovarian stimulation.read more
Citations
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American association of clinical endocrinologists and american college of endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity.
W. Timothy Garvey,Jeffrey I. Mechanick,Elise M. Brett,Alan J. Garber,Daniel L. Hurley,Ania M. Jastreboff,Karl Nadolsky,Rachel Pessah-Pollack,Raymond A Plodkowski +8 more
TL;DR: The final recommendations recognize that obesity is a complex, adiposity-based chronic disease, where management targets both weight-related complications and adiposity to improve overall health and quality of life.
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Anti-Müllerian hormone (AMH) as a predictive marker in assisted reproductive technology (ART)
A. La Marca,Giovanna Sighinolfi,D Radi,Cindy Argento,Enrica Baraldi,A. Carducci Artenisio,Gaspare Stabile,Annibale Volpe +7 more
TL;DR: AMH seems to be a better marker in predicting ovarian response to controlled ovarian stimulation than age of the patient, FSH, estradiol and inhibin B, and a similar performance for AMH and antral follicular count has been reported.
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The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment: a review
TL;DR: It is concluded that lifestyle modification can assist couples to conceive spontaneously or optimize their chances of conception with ART treatment.
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Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence
TL;DR: There is evidence that obesity may increase the general risk of miscarriage, however, there is insufficient evidence to describe the effect of obesity on miscarriage in specific groups such as those conceiving after assisted conception.
Journal ArticleDOI
Effect of overweight and obesity on assisted reproductive technology—a systematic review
TL;DR: There is insufficient evidence on the effect of BMI on live birth, cycle cancellation, oocyte recovery and ovarian hyperstimulation syndrome, and further studies with clear entry criteria and uniform reporting of outcomes are needed to investigate the true impact of weight.
References
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