Impact of overweight and underweight on assisted reproduction treatment
Peter Fedorcsak,Per Olav Dale,Ritsa Storeng,Gudvor Ertzeid,Sverre Bjercke,Nan B. Oldereid,Anne Katerine Omland,Thomas Åbyholm,Tom Tanbo +8 more
TLDR
Obesity is associated with lower chances for live birth after IVF and ICSI and with an impaired response to ovarian stimulation and with a increased risk of early pregnancy loss occurring before 6 weeks gestation.Abstract:
RESULTS: The cumulative live birth rate within three treatment cycles was 41.4% [95% confidence interval (CI) 32.1– 50.7] in obese women with BMI $30 kg/m 2 and 50.3 (95% CI 47.0–53.7) in normal weight women with BMI 18.5– 24.9 kg/m 2 . Obesity was associated with an increased risk of early pregnancy loss occurring before 6 weeks gestation. Positive correlation between BMI and gonadotrophin requirement during stimulation and negative correlation between BMI and number of collected oocytes were observed. Underweight (BMI < 18.5 kg/m 2 ) was not related to an impaired outcome of IVF or ICSI. CONCLUSIONS: Obesity is associated with lower chances for live birth after IVF and ICSI and with an impaired response to ovarian stimulation.read more
Citations
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South Asian women with polycystic ovary syndrome exhibit greater sensitivity to gonadotropin stimulation with reduced fertilization and ongoing pregnancy rates than their Caucasian counterparts.
TL;DR: The Asian PCOS have a greater sensitivity to gonadotropin stimulation with lower fertilization and ongoing clinical pregnancy rates as compared with their Caucasian counterparts, and South Asian women presented at a younger age for the management of sub-fertility.
Journal ArticleDOI
Risk factors for unexplained recurrent spontaneous abortion in a population from southern China.
TL;DR: To determine risk factors for recurrent spontaneous abortion (RSA) in women from southern China, a large number of women from this region have had at least one abortion.
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Surrogate obesity negatively impacts pregnancy rates in third-party reproduction.
TL;DR: It is observed that surrogate body mass index negatively impacts implantation rates in oocyte-donor in vitro fertilization cycles and a BMI > or =35 kg/m(2) cutoff is associated with a statistically significant decrease in pregnancy rates but not miscarriage rates.
Journal ArticleDOI
Obesity and its relationship to infertility in men and women.
TL;DR: This review focuses on the negative impact of obesity in reproduction by considering the pathophysiology of obesity and infertility in men and women, the influence of obesity on the prevalence of polycystic ovary syndrome, and the benefits of weight loss on reproduction and on menstruation, ovulation, semen parameters, and reproductive outcomes.
Journal ArticleDOI
Obesity and reproduction: a committee opinion
Alan S. Penzias,Ricardo Azziz,Kristin Bendikson,Tommaso Falcone,Karl R. Hansen,Micah J. Hill,Sangita Jindal,Suleena Kansal Kalra,Jennifer Mersereau,Richard H. Reindollar,Chevis N. Shannon,Anne Z. Steiner,Cigdem Tanrikut,Hugh S. Taylor,Belinda J. Yauger +14 more
TL;DR: The purpose of this American Society for Reproductive Medicine Practice Committee report is to provide clinicians with principles and strategies for the evaluation and treatment of couples with infertility associated with obesity as mentioned in this paper.
References
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