In vivo 31P-NMR diffusion spectroscopy of ATP and phosphocreatine in rat skeletal muscle
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TLDR
The modelling suggests that the in vivo restriction of ATP and PCr diffusion is not imposed by the sarcolemma but by other, intracellular structures with an overall cylindrical orientation.About:
This article is published in Biophysical Journal.The article was published on 2000-04-01 and is currently open access. It has received 119 citations till now. The article focuses on the topics: Phosphocreatine.read more
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Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis.
TL;DR: Astrocytic energy demand is stimulated by K+ and glutamate uptake, signaling processes, responses to neurotransmitters, Ca2+ fluxes, and filopodial motility, which contributes to the decreased oxygen to glucose utilization ratio during brain activation.
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Axonal mitochondrial transport and potential are correlated.
Kyle E. Miller,Michael P. Sheetz +1 more
TL;DR: These experiments show for the first time that a uniform mitochondrial distribution is generated by local regulation of the stopping events of fast mitochondrial transport, and that the direction of mitochondrial transport is correlated with mitochondrial potential.
Book
NMR Studies of Translational Motion
TL;DR: A detailed discussion of magnetic field gradient methods applied to Magnetic Resonance Imaging (MRI) is included, alongside extensive referencing throughout, providing a timely, definitive book to the subject, ideal for researchers in the fields of physics, chemistry and biology.
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Cardiac system bioenergetics: metabolic basis of the Frank‐Starling law
TL;DR: Advances made in understanding of complex cellular and molecular mechanisms that orchestrate coupling of mitochondrial oxidative phosphorylation with ATP utilization for muscle contraction are highlighted.
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Redox Signaling by Reactive Electrophiles and Oxidants
TL;DR: This Review reflects on five aspects critical for understanding how nature harnesses these noncanonical post-translational modifications to coordinate distinct cellular activities: specific players and their generation, physicochemical properties, mechanisms of action, methods of interrogation, and functional roles in health and disease.
References
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Spin diffusion measurements : spin echoes in the presence of a time-dependent field gradient
E. O. Stejskal,J. E. Tanner +1 more
TL;DR: In this article, a derivation of the effect of a time-dependent magnetic field gradient on the spin-echo experiment, particularly in the presence of spin diffusion, is given.
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MR diffusion tensor spectroscopy and imaging.
TL;DR: Once Deff is estimated from a series of NMR pulsed-gradient, spin-echo experiments, a tissue's three orthotropic axes can be determined and the effective diffusivities along these orthotropic directions are the eigenvalues of Deff.
Journal ArticleDOI
Book Review: NMR Basic principles and progress. Vol. 6, P. Diehl (Universität Basel), E. Fluck (Universität Stuttgart), and R. Kosfeld (Technische Hochschule Aachen). Computer Assistance in the Analysis of High Resolution NMR Spectra, by P. Diehl and H. Kellerhals (Universität Basel) and E. Lustig (Food and Drug Administration, U.S.A.). Springer—Verlag, Heidelberg. 1972. 96 pp. $15.30
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Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis.
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Determination of intracellular pH by 31P magnetic resonance.
Richard B. Moon,John H. Richards +1 more
TL;DR: Observation of the ^(31)P signal from various intracellular phosphates can provide a convenient, nondestructive technique for determining intrace cellular conditions such as pH.
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