Journal ArticleDOI
Incorporation and controlled release of a hydrophilic antibiotic using poly(lactide-co-glycolide)-based electrospun nanofibrous scaffolds
Kwangsok Kim,Yen K. Luu,Charles Chang,Dufei Fang,Benjamin S. Hsiao,Benjamin Chu,Michael Hadjiargyrou +6 more
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TLDR
The combination of mechanical barriers based on non-woven nanofibrous biodegradable scaffolds and their capability for local delivery of antibiotics increases their desired utility in biomedical applications, particularly in the prevention of post-surgical adhesions and infections.About:
This article is published in Journal of Controlled Release.The article was published on 2004-07-23. It has received 760 citations till now. The article focuses on the topics: Controlled release & Drug delivery.read more
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Electrospinning: a fascinating fiber fabrication technique.
Nandana Bhardwaj,Subhas C. Kundu +1 more
TL;DR: This review presents an overview of the electrospinning technique with its promising advantages and potential applications, and focuses on varied applications of electrospun fibers in different fields.
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Electrospinning: A Fascinating Method for the Preparation of Ultrathin Fibers
TL;DR: Electrospinning is a highly versatile method to process solutions or melts, mainly of polymers, into continuous fibers with diameters ranging from a few micrometers to a few nanometers, applicable to virtually every soluble or fusible polymer.
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Electrospinning: Applications in drug delivery and tissue engineering
TL;DR: This review summarizes the most recent and state of the art work in electrospinning and its uses in tissue engineering and drug delivery and its ability to fabricate fibers with diameters on the nanometer size scale.
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A comprehensive review summarizing the effect of electrospinning parameters and potential applications of nanofibers in biomedical and biotechnology
TL;DR: In this paper, the authors provide an overview of the electrospinning (applied electric field, distance between the needle and collector and flow rate, needle diameter), solution (polymer concentration, viscosity, solvent and solution conductivity) and environmental (relativity humidity and temperature) parameters that affect the nanofibers fabrication.
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Electrospinning of polymeric nanofibers for drug delivery applications
TL;DR: The inherently high surface to volume ratio of electrospun fibers can enhance cell attachment, drug loading, and mass transfer properties of these fibers.
References
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Staphylococcus aureus infections.
TL;DR: In an elegant series of clinical observations and laboratory studies published in 1880 and 1882, Ogston described staphylococcal disease and its role in sepsis and abscess formation.
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Electrospinning process and applications of electrospun fibers
Jayesh Doshi,Darrell H. Reneker +1 more
TL;DR: In this article, the authors describe the electrospinning process, the processing conditions, fiber morphology, and some possible uses of electrospun fibers, and describe the diameter of these fibers in the range of 0.05 to 5 microns.
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Biodegradable long-circulating polymeric nanospheres
Ruxandra Gref,Yoshiharu Minamitake,Maria Teresa Peracchia,Vladimir S. Trubetskoy,Vladimir P. Torchilin,Robert Langer +5 more
TL;DR: Monodisperse biodegradable nanospheres were developed from amphiphilic copolymers composed of two biocompatible blocks and exhibited dramatically increased blood circulation times and reduced liver accumulation in mice.
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New methods of drug delivery.
TL;DR: Conventional forms of drug administration generally rely on pills, eye drops, ointments, and intravenous solutions, but a number of novel drug delivery approaches have been developed, which may revolutionize the way many drugs are delivered.
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Beaded nanofibers formed during electrospinning
TL;DR: The viscoelasticity of the solution, charge density carried by the jet, and the surface tension of the polymer solution are the key factors that influence the formation of the beaded fibers as discussed by the authors.