Journal ArticleDOI
Influence of eye colors of Caucasians and Asians on suppression of melatonin secretion by light
TLDR
The results suggest that sensitivity of melatonin to light suppression is influenced by eye pigmentation and/or ethnicity.Abstract:
This experiment tested effects of human eye pigmentation depending on the ethnicity on suppression of nocturnal melatonin secretion by light. Ten healthy Caucasian males with blue, green, or light ...read more
Citations
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Journal ArticleDOI
Light-at-night, circadian disruption and breast cancer: assessment of existing evidence
TL;DR: If a consensus eventually emerges that LAN does increase risk, then the mechanisms for the effect are important to elucidate for intervention and mitigation and will provide for the development of lighting technologies at home and at work that minimize circadian disruption, while maintaining visual efficiency and aesthetics.
Journal ArticleDOI
Circadian photoreception: ageing and the eye’s important role in systemic health
TL;DR: Non-visual retinal ganglion photoreceptor responses to bright, properly timed light exposures help assure effective circadian photoentrainment and optimal diurnal physiological processes.
Journal ArticleDOI
Night-Shift Work and Breast Cancer Risk in a Cohort of Chinese Women
Anjoeka Pronk,Bu Tian Ji,Xiao-Ou Shu,Shouzheng Xue,Gong Yang,Hong Lan Li,Nathaniel Rothman,Yu-Tang Gao,Wei Zheng,Wong Ho Chow +9 more
TL;DR: The lack of an association between night-shift work and breast cancer adds to the inconsistent epidemiologic evidence and it may be premature to consider shift work a cause of cancer.
Journal ArticleDOI
Exposure to bright light and darkness to treat physiologic maladaptation to night work
Journal ArticleDOI
Post-illumination pupil response in subjects without ocular disease.
TL;DR: All normal subjects displayed a significant PIPR for a 10-second, 470-nm light stimulus, but not a 623-nm stimulus, which is consistent with the proposed melanopsin-mediated response.
References
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Journal Article
A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms.
James Horne,Ostberg O +1 more
TL;DR: Although the questionnaire appears to be valid, further evaluation using a wider subject population is required, as sleep habits are an important déterminant of peak time there are other contibutory factors, and these appear to be partly covered by the questionnaire.
Journal ArticleDOI
Phototransduction by retinal ganglion cells that set the circadian clock.
TL;DR: It is shown that retinal ganglion cells innervating the SCN are intrinsically photosensitive, and depolarized in response to light even when all synaptic input from rods and cones was blocked.
Journal ArticleDOI
Light Suppresses Melatonin Secretion in Humans
TL;DR: Findings establish that the human response to light is qualitatively similar to that of other mammals.
Journal ArticleDOI
Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression
Jamie M. Zeitzer,Jamie M. Zeitzer,Derk-Jan Dijk,Richard E. Kronauer,Richard E. Kronauer,Richard E. Kronauer,Emery N. Brown,Emery N. Brown,Emery N. Brown,Charles A. Czeisler,Charles A. Czeisler,Charles A. Czeisler +11 more
TL;DR: It is demonstrated that humans are highly responsive to the phase‐delaying effects of light during the early biological night and that both the phase resetting response to light and the acute suppressive effect of light on plasma melatonin follow a logistic dose‐response curve, as do many circadian responses to light in mammals.
Journal ArticleDOI
High sensitivity of human melatonin, alertness, thermoregulation, and heart rate to short wavelength light.
Christian Cajochen,Mirjam Münch,Szymon Kobialka,Kurt Kräuchi,Roland Steiner,Peter Oelhafen,Selim Orgül,Anna Wirz-Justice +7 more
TL;DR: The findings-that the sensitivity of the human alerting response to light and its thermoregulatory sequelae are blue-shifted relative to the three-cone visual photopic system-indicate an additional role for these novel photoreceptors in modifying human alertness, thermophysiology, and heart rate.
Related Papers (5)
Phototransduction by retinal ganglion cells that set the circadian clock.
An action spectrum for melatonin suppression: evidence for a novel non‐rod, non‐cone photoreceptor system in humans
A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms.
James Horne,Ostberg O +1 more