Proceedings ArticleDOI
Interaction of focused ultrasound with biological materials
Ajit Mal,Feng Feng,Michael Kabo,Jeffrey C. Wang,Yoseph Bar-Cohen +4 more
- Vol. 4702, pp 339-348
TLDR
In this article, a finite element-based program called PZflex is used to calculate the mechanical and thermal effects caused by high-frequency ultrasound in different material systems, and the pressure distributions generated by plane and focused ultrasound beams are presented.Abstract:
This work is motivated by possible medical applications of focused ultrasound in minimally invasive treatment of a variety of disorders. The mechanical and thermal effects caused by high-frequency ultrasound in different material systems are calculated using a finite element based program called PZflex. The pressure distributions generated by plane as well as focused ultrasound beams are presented. For the focused beam, the temperature distribution in the focal zone is also calculated. The results indicate that the heating efficiency of the ultrasound energy in the focal region depends on the exciting frequency and the geometry of the focal zone depends on the material being tested. At higher excitation energies, cavitation and nonlinear effects need to be included in the simulations. These effects are under current investigation.© (2002) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.read more
Citations
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Evaluation of laser spallation as a technique for measurement of cell adhesion strength
TL;DR: This study investigates the possibility of using laser spallation, a technique previously developed for measuring the tensile strength of thin film interfaces, for evaluation of initial cell attachment strength, and found Absolute values of adhesion strengths determined by laser Spallation were significantly higher than those found using jet impingement.
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Measurement of the tensile strength of cell-biomaterial interface using the laser spallation technique.
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Journal ArticleDOI
Laser induced plane acoustic wave generation, propagation, and interaction with rigid structures in water
Seung Hwan Ko,Sang G. Ryu,Nipun Misra,Heng Pan,Costas P. Grigoropoulos,Nick Kladias,Elias Panides,Gerald A. Domoto +7 more
TL;DR: In this article, a short pulsed laser induced single plane acoustic wave generation, propagation, interaction with rigid structures, and focusing in water are experimentally and numerically studied, and the results demonstrate that the laser induced planar acoustic wave can be focused down to several tens of micron size and several bars in pressure.
Proceedings ArticleDOI
Pressure and temperature distribution in biological tissues by focused ultrasound
TL;DR: In this article, the effects of nonlinearities on the pressure and temperature distribution induced by focused ultrasound in a two-dimensional model were investigated. And a comparison of the results between linear and nonlinear cases is reported.
References
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Noninvasive real-time multipoint temperature control for ultrasound phased array treatments
TL;DR: In this article, a method for noninvasively estimating spatiotemporal temperature changes in samples using diagnostic ultrasound, and using these as inputs to a multipoint ultrasound phased array temperature controller, is presented.
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Noninvasive surgery of prostate tissue by high-intensity focused ultrasound
Narendra T. Sanghvi,F.J. Fry,Richard Bihrle,Richard S. Foster,M.H. Phillips,J. Syrus,A.V. Zaitsev,Carl W. Hennige +7 more
TL;DR: This paper reviews major steps progressing from conception to the present clinical trial status of the HIFU device and results of human clinical studies are summarized to indicate performance of the device.
Proceedings ArticleDOI
Nonlinear modeling of therapeutic ultrasound
TL;DR: In this article, the authors describe experimental finite element modeling of tissue ablation by focused ultrasound, focusing on nonlinear coupling of high intensity sound temperature, and tissue properties, using an incrementally linear, time-domain, finite element algorithm solving the electromechanical and bioheat equations.