scispace - formally typeset
Open AccessJournal ArticleDOI

Juvenile and juvenile-onset systemic lupus erythematosus patients: Clinical characteristics, disease activity and damage

Reads0
Chats0
TLDR
Differences in clinical phenotype has been confirmed, between JSLE and JO-SLE especially as regards serositis, nephritis and heamatological affection and the disease damage was comparable which denotes that the maximum organ involvement occurs in childhood with an almost stationary course.
About
This article is published in Egyptian Pediatric Association Gazette.The article was published on 2017-07-01 and is currently open access. It has received 6 citations till now. The article focuses on the topics: Anti-SSA/Ro autoantibodies & Serositis.

read more

Citations
More filters
Journal ArticleDOI

Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus

TL;DR: The presence of headache, mood disorders, psychosis, depression, and other neuropsychological manifestations in a patient with JSLE should prompt investigations into diagnosis of the primary nervous system involvement in order to reduce mortality and morbidity.
Journal ArticleDOI

Clinical features, disease activity and outcomes of Malaysian children with paediatric systemic lupus erythematosus: A cohort from a tertiary centre:

TL;DR: Despite high disease activity at diagnosis, the majority had good sustained response to treatment with low overall mortality, however, there was progressive accrual of organ damage, highlighting the need for further research and refinements into therapies for paediatric systemic lupus erythematosus.
Journal ArticleDOI

Elevated serum interleukin-34 level in juvenile systemic lupus erythematosus and disease activity.

TL;DR: IL-34 could be a probable marker for J-Sle disease activity which is more aggressive than adult-SLE, and IL-34 blockage may suppress the expression of proinflammatory cytokines in patients’ blood.
Journal ArticleDOI

A Preliminary Predictive Model for Proliferative Lupus Nephritis in Juvenile Systemic Lupus Erythematosus

TL;DR: In this article , a clinical predictive machine learning model using routine standard parameters as an alternative tool to evaluate the probability of proliferative lupus nephritis (ISN/RPS Class III or IV) was developed.
References
More filters
Journal ArticleDOI

Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE.

TL;DR: The development of the SLEDAI is described, a validated model of experienced clinicians' global assessments of disease activity in lupus, which represents the consensus of a group of experts in the field of l upus research.
Journal ArticleDOI

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus.

Michelle Petri, +51 more
TL;DR: The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new knowledge regarding the immunology of SLE.
Book

Renal Disease: Classification and Atlas of Glomerular Diseases

TL;DR: An atlas that is really an atlas: an encyclopedic collection of electron micrographs, stained sections (including immunofluorescent stains), and diagrams that primarily illustrate renal diseases and systemic diseases with renal lesions.
Related Papers (5)