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Lactated Ringer's solution reduces systemic inflammation compared with saline in patients with acute pancreatitis.

TLDR
Patients with acute pancreatitis who were resuscitated with lactated Ringer's solution had reduced systemic inflammation compared with those who received saline.
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This article is published in Clinical Gastroenterology and Hepatology.The article was published on 2011-08-01. It has received 421 citations till now. The article focuses on the topics: Resuscitation & Ringer's solution.

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Citations
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American College of Gastroenterology guideline: management of acute pancreatitis.

TL;DR: As the diagnosis of AP is most often established by clinical symptoms and laboratory testing, contrast-enhanced computed tomography and/or magnetic resonance imaging of the pancreas should be reserved for patients in whom the diagnosis is unclear or who fail to improve clinically.

Acute pancreatitis

TL;DR: There is a wide spectrum of disease from mild (80%), where patients recover within a few days, to severe (20%) with prolonged hospital stay, the need for critical care support, and a 15-20% risk of death.
Journal ArticleDOI

IAP/APA evidence-based guidelines for the management of acute pancreatitis

H. van Goor
- 01 Jan 2013 - 
TL;DR: The 2012 IAP/APA guidelines provide recommendations concerning key aspects of medical and surgical management of acute pancreatitis based on the currently available evidence that should serve as a reference standard for current management and guide future clinical research on acute Pancreatitis.
Journal ArticleDOI

The Science and Translation of Lactate Shuttle Theory

TL;DR: Clinical studies are utilizing lactate to treat pro-inflammatory conditions and to deliver optimal fuel for working muscles in sports medicine and "Lactate shuttle" concepts describe the roles of lactate in delivery of oxidative and gluconeogenic substrates as well as in cell signaling.
References
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CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials

TL;DR: The Consort 2010 Statement as discussed by the authors has been used worldwide to improve the reporting of randomised controlled trials and has been updated by Schulz et al. in 2010, based on new methodological evidence and accumulating experience.
Journal ArticleDOI

CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials

TL;DR: The 2010 version of the CONSORT Statement is described, which updates the previous reporting guideline based on new methodological evidence and accumulated experience.
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