Leptospirosis from water sources
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TLDR
The ability of leptospires to survive in moist environments makes them a high-risk agent for infection following contact with any contaminated water source, and there are many differences in water treatment systems around the world, particularly between developing and developed countries.Abstract:
Leptospirosis outbreaks have been associated with many common water events including water consumption, water sports, environmental disasters, and occupational exposure. The ability of leptospires to survive in moist environments makes them a high-risk agent for infection following contact with any contaminated water source. Water treatment processes reduce the likelihood of leptospirosis or other microbial agents causing infection provided that they do not malfunction and the distribution networks are maintained. Notably, there are many differences in water treatment systems around the world, particularly between developing and developed countries. Detection of leptospirosis in water samples is uncommonly performed by molecular methods.read more
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Harrison's Principles of Internal Medicine
TL;DR: The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors.
Journal ArticleDOI
Characterization of bacterial communities in wastewater with enhanced taxonomic resolution by full-length 16S rRNA sequencing.
Daniela Numberger,Lars Ganzert,Luca Zoccarato,Kristin Mühldorfer,Sascha Sauer,Hans-Peter Grossart,Hans-Peter Grossart,Alex D. Greenwood,Alex D. Greenwood +8 more
TL;DR: Describing and compared the bacterial community of the inflow and effluent of a WWTP in Berlin, Germany using full-length 16S rRNA gene sequences allows for improved characterization of potential pathogenic taxa and other harmful bacteria which is required to reliably assess health risk.
Journal ArticleDOI
Major epidemiological factors associated with leptospirosis in Malaysia
Bashiru Garba,Abdul Rani Bahaman,Siti Khairani Bejo,Zunita Zakaria,Abdul Rahim Mutalib,Faruku Bande +5 more
TL;DR: There is an urgent need for the government and other stakeholders to intensify efforts to control the spread of leptospirosis, especially as it greatly affect human health and the tourism industry which is an important component of the Malaysian economy.
Journal ArticleDOI
Freshwater monitoring by nanopore sequencing
Lara Urban,Andre Holzer,J. Jotautas Baronas,Michael B Hall,Philipp Braeuninger-Weimer,Michael J Scherm,Daniel J Kunz,Daniel J Kunz,Surangi N. Perera,Daniel E. Martin-Herranz,Edward T. Tipper,Susannah J. Salter,Maximilian R Stammnitz +12 more
TL;DR: The MinION as mentioned in this paper is a pocket-sized device that can sequence genetic information on-the-go and can be used to detect bacterial species present in rivers, which has been used to monitor water quality in remote areas.
Posted ContentDOI
Freshwater monitoring by nanopore sequencing
Lara Urban,Andre Holzer,J. Jotautas Baronas,Michael B Hall,Philipp Braeuninger-Weimer,Michael J Scherm,Daniel J Kunz,Daniel J Kunz,Surangi N. Perera,Daniel E. Martin-Herranz,Edward T. Tipper,Susannah J. Salter,Maximilian R Stammnitz +12 more
TL;DR: It is found that nanopore metagenomics can depict the hydrological core microbiome and fine temporal gradients in line with complementary physicochemical measurements, and is anticipated that this framework will gather momentum for new environmental monitoring initiatives using portable devices.
References
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TL;DR: The recent development of defined mutagenesis systems for Leptospira heralds the potential for gaining a much improved understanding of pathogenesis in leptospirosis, and shows promise for the development of vaccines based on defined protective antigens.
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Microbial contamination of drinking water and disease outcomes in developing regions.
TL;DR: Drinking water is a major source of microbial pathogens in developing regions, although poor sanitation and food sources are integral to enteric pathogen exposure, and various enteroviruses, C. jejuni and H. pylori are emerging issues in adults.