Journal ArticleDOI
Leuprolide acetate depot and hormonal add-back in endometriosis: A 12-month study
TLDR
The use of leuprolide acetate depot in combination with norethindrone acetate 5 mg alone, or with noredouble acetate and conjugated equine estrogens 0.625 mg, provides effective suppression of pelvic pain symptoms associated with endometriosis while protecting against bone loss.About:
This article is published in Obstetrics & Gynecology.The article was published on 1998-01-01. It has received 210 citations till now. The article focuses on the topics: Norethindrone Acetate & Progestin.read more
Citations
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Journal ArticleDOI
Clinical practice. endometriosis
TL;DR: A healthy 25-year-old woman presents with worsening dysmenorrhea, pain of recent onset in the left lower quadrant, and dyspareunia.
Journal ArticleDOI
Chronic pelvic pain.
TL;DR: Treatment of chronic pain as well as treatment of four of the more common disorders associated with chronic pelvic pain (endometriosis, adhesions, irritable bowel syndrome, and interstitial cystitis) are discussed in this review.
PatentDOI
Treatment of endometriosis
TL;DR: The extent of the pain is influenced primarily by the location and depth of the endometriotic implant, with deep implants in highly innervated areas most consistently associated with pain.
Journal ArticleDOI
Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist
Hugh S. Taylor,Linda C. Giudice,Bruce A. Lessey,Mauricio Simões Abrão,J. Kotarski,David F. Archer,Michael P. Diamond,Eric S. Surrey,Neil P. Johnson,Nelson B. Watts,J. C. Gallagher,James A. Simon,Bruce R. Carr,W. P. Dmowski,Nicholas Leyland,J.P. Rowan,W.R. Duan,Juki Ng,B. Schwefel,Jacqueline Thomas,Rita Jain,Kristof Chwalisz +21 more
TL;DR: Both higher and lower doses of elagolix were effective in improving dysmenorrhea and nonmenstrual pelvic pain during a 6‐month period in women with endometriosis‐associated pain.
References
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Journal ArticleDOI
Effects of Estrogen or Estrogen/ Progestin Regimens on Heart Disease Risk Factors in Postmenopausal Women: The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
Valery T. Miller,John C. LaRosa,Vanessa M. Barnabei,Craig M. Kessler,Ginny Levin,Ann Smith-Roth,Margaret Griffin,Diane B. Stoy,Trudy L. Bush,Howard A. Zacur,David A. Foster,Jean Anderson,Alice McKenzie,Susan C. Miller,Peter D. Wood,Marcia L. Stefanick,Robert Marcus,Allison Akana,W. Leroy Heinrichs,Charlene Kirchner,Katherine A. O'Hanlan,Melissa Ruyle,Mary A. Sheehan,Howard L. Judd,Gail A. Greendale,Richard Bayalos,Kathy Lozano,Kathy Kawakami,Elizabeth Barrett-Connor,Robert Langer,Donna Kritz-Silverstein,Mary Lou Carrion-Petersen,Carmela Cavero,Helmut G. Schrott,Susan R. Johnson,Deborah A. Feddersen,Denise L. Krutzfeldt,Jo Ann Benda,Carl J. Pauerstein,Jose Trabal,Robert S. Schenken,Michael P. Stern,Mercedes Rodriguez-Sifuentes,Carann Easton,H B Wells,Mark A. Espeland,George Howard,Robert Byington,Claudine Legault,Sally A. Shumaker,Patricia E. Hogan,Don Hire,Carol Wasilauskas,Margaret K. James,Kathy Lane,Tim Terrell,Stephanie Reece,June J Pierce,Mary Snow,Susan Anthony,Irma Mebane-Sims,Paula T. Einhorn,Sally Hunsberger,Myron A. Waclawiw,Ken Lippel,Diane L. Lucas,Joel Verter,Sherry Jackson,Joseph Kelaghan,Jeffrey M. Perlman,Pam Wolf,Joan McGowan,Stephen Gordon,Stephen Heyse,Judith E. Fradkin,Sherry Sherman,Lot B. Page,Ann Sorenson,Barbara S. Hulka,Baruch A. Brody,Ronald T. Burkman,Robert P. Heaney,Ronald M. Krauss,Harold Roberts,Janet Wittes,Lawrence Riggs,Richard Moss,John J. Albers,Santica M. Marcovina,S. Edwin Fineberg,Russell P. Tracy,Maria J. Merino,Robert E. Scully,Virginia A. LiVolsi,Gerald Kessler +94 more
TL;DR: Estrogen alone or in combination with a progestin improves lipoproteins and lowers fibrinogen levels without detectable effects on postchallenge insulin or blood pressure and in women with a uterus, CEE with cyclic MP has the most favorable effect on HDL-C and no excess risk of endometrial hyperplasia.
Journal Article
Revised American Fertility Society classification of endometriosis: 1985
W. C. Andrews,V. C. Buttram,S. J. Behrman,E. Carmichael,M. R. Cohen,P. Dmowski,R. D. Eward,David S. Guzick,H. W. Jones,R. W. Kistner,J. C. Weed,Charles B. Hammond,H. H. Thomas +12 more
Journal ArticleDOI
Long-Term Estrogen Replacement Therapy Prevents Bone Loss and Fractures
TL;DR: In this article, a retrospective study was done comparing the occurrence of fractures in 245 long-term estrogen users and 245 case-matched controls, followed for an average of 17.6 years.
Journal ArticleDOI
Post-menopausal oestrogens protect against fractures of hip and distal radius. A case-control study.
TL;DR: In this article, the efficacy of oestrogens in preventing the common major limb fractures of postmenopausal women, retrospective case-control research was used for a new purpose to explore a beneficial rather than adverse effect of treatment.
Journal ArticleDOI
Administration of nasal nafarelin as compared with oral danazol for endometriosis. A multicenter double-blind comparative clinical trial.
Milan R. Henzl,Stephen L. Corson,Kamran Moghissi,Veasy C. Buttram,Christer Berqvist,Jan J. Jacobson +5 more
TL;DR: It is concluded that nafarelin is an effective agent for treating endometriosis and has few side effects other than hypoestrogenism.