Lipid Material for the Preparation of Microsphere Challenges and Recent Advancement A Review

TLDR: This paper deals with study about the role of different lipid material and their used in pharmaceutical formulations and emphasizes on recent patents based on lipid material based pharmaceutical preparations.

Abstract: Lipid is a water insoluble biomolecule. It is soluble in nonpolar organic solvent. These are made up of fatty acids. Lipids are group of natural molecules such as vitamins etc. Fatty acids are the part of lipid and fatty acid are synthesized by chain elongation acetylacetyl-CoA primer with malonyl-CoA or methylmalonyl- CoA groups in a process called fatty acid synthesis. Glycerolipids are composed of mono-, di- and tri- substituted glycerols. Glycerophospholipids involved in metabolism and cell signaling. Sphingolipids base backbone that is synthesized de novo from the amino acid serine and a long-chain fatty acyl CoA. Polyketides are synthesized by polymerization of acetyl and propionyl subunits by classic enzymes as well as iterative and multimodular enzymes that share mechanistic features with the fatty acid synthesis. This paper deals with study about the role of different lipid material and their used in pharmaceutical formulations. Manuscript also emphasize on recent patents based on lipid material based pharmaceutical preparations.