Journal ArticleDOI
Pineal gland: influence on gonads of male hamsters.
TLDR
Data emphasize the importance of the pineal gland in the regulation of photoperiodic influences on the gonads in hamsters exposed to light-dark cycles.Abstract:
Exposure of male hamsters to cycles of 1 hour of light and 23 hours of darkness causes atrophy of the gonads. Pinealectomy prevents this atrophy, but has no effect on animals exposed to light-dark cycles of 16 : 8. Likewise, removal of both eyes induces gonad atrophy which is prevented by pinealectomy. These data emphasize the importance of the pineal gland in the regulation of photoperiodic influences on the gonads.read more
Citations
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Journal ArticleDOI
Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*
TL;DR: The pineal gland can be rapidly removed from rodents with minimal damage to adjacent neural structures using a specially designed trephine, and since the mid 1960s, research on the gland has become a very active area of investigation.
Journal ArticleDOI
Melatonin as an antioxidant: under promises but over delivers.
Russel J. Reiter,Juan C. Mayo,Dun Xian Tan,Rosa M. Sainz,Moisés Alejandro Alatorre-Jiménez,Lilian Qin +5 more
TL;DR: It is the current feeling of the authors that, in view of the widely diverse beneficial functions that have been reported for melatonin, these may be merely epiphenomena of the more fundamental, yet‐to‐be identified basic action(s) of this ancient molecule.
Journal ArticleDOI
The melatonin rhythm: both a clock and a calendar.
TL;DR: The paper summarizes the 3 patterns of nocturnal melatonin production that have been described and shows that the circadian production and secretion of melatonin by the pineal gland can impart both daily and seasonal, i.e., calendar, information to the organism.
Journal ArticleDOI
Extrapineal melatonin: sources, regulation, and potential functions.
Darío Acuña-Castroviejo,Germaine Escames,Carmen Venegas,María E. Díaz-Casado,Elena Lima-Cabello,Luis C. López,Sergio Rosales-Corral,Dun Xian Tan,Russel J. Reiter +8 more
TL;DR: The presence of melatonin in extrapineal organs, tissues, and fluids of mammals including humans is emphasized and information related to its peripheral production and regulation of this ubiquitously acting indoleamine is compiled.
Journal ArticleDOI
Mammalian Photoperiodic System: Formal Properties and Neuroendocrine Mechanisms of Photoperiodic Time Measurement
TL;DR: Variations in photoperiodic response are seen not only between species but also between breeding populations within a species and between individuals within single breeding populations, and among species differences with respect to the importance and specific functions of various melatonin target sites.
References
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Journal ArticleDOI
Handbook of Physiology.
TL;DR: This is the first volume of the proposed many-sectioned "Handbook" in which the American Physiological Society intends to present comprehensively the entire field of physiology.
Journal ArticleDOI
Melatonin, a pineal substance: effect on the rat ovary.
TL;DR: Daily injection of microgram amounts of melatonin in rats decreased the incidence of estrus and reduced ovarian weight and Circulating melatonin was selectively taken up and retained by the ovary and pineal gland.
Journal ArticleDOI
Effects of pinealectomy and of a bovine pineal extract in rats.
TL;DR: Giving the extract of a protein-free bovine pineal extract to intact animals caused effects varying with the dose, which reversed changes in ovarian hypertrophy, pituitary hyperTrophy, and adrenalhypertrophy.
Journal ArticleDOI
Effecr of light and temperature on the endocrine system of the golden hamster Mesocricetus auratus waterhouse)
TL;DR: Exposure of male hamster to short photoperiods or low temperatures for 2, 4 and 6 weeks inhibits normal increases in body weight, atrophy of the gonads characterized by increased cholesterol concentration, and by histological and histochemical appearance, and an increase in brown fat weight.
Journal ArticleDOI
Interactions of the pineal and exposure to continuous light on organ weights of female rats.
TL;DR: The data suggest that the effect of light upon the weight of the ovary is mediated via the pineal, and that pinealectomy did not share with light-exposure the capacity to induce uterine hypertrophy.