Journal ArticleDOI
Long-term effect of inhaled budesonide in mild and moderate chronic obstructive pulmonary disease: a randomised controlled trial
Jøorgen Vestbo,Jøorgen Vestbo,Torben Søorensen,Peter Lange,Peter Lange,Anders Brix,Piero Torre,Kaj Viskum +7 more
TLDR
Inhaled budesonide was of no clinical benefit in COPD patients recruited from the general population by screening and the role of long-term inhaled corticosteroids in the treatment of mild to moderate COPD is questioned.About:
This article is published in The Lancet.The article was published on 1999-05-29. It has received 802 citations till now. The article focuses on the topics: Budesonide & COPD.read more
Citations
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Journal ArticleDOI
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
Jørgen Vestbo,Suzanne S. Hurd,Alvar Agusti,Paul W. Jones,Claus Vogelmeier,Antonio Anzueto,Peter J. Barnes,Leonardo M. Fabbri,Fernando J. Martinez,Masaharu Nishimura,Robert A. Stockley,Don D. Sin,Roberto Rodriguez-Roisin +12 more
TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
Journal ArticleDOI
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary.
TL;DR: List of participants (GOLD Scientific Committee): Nicholas Anthonisen, Winnipeg, Canada, William C. Bailey, Birmingham, US, Tim Clark, London, UK, Leonardo Fabbri, Modena, Italy, Yoshinosuke Fukuchi, Tokyo, Japan; Lawrence Grouse, Seattle, US; James C. Hogg, Vancouver, Canada; Dirkje S. Postma, Groningen, the Netherlands.
Journal ArticleDOI
Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper
Bartolome R. Celli,William MacNee,Alvar Agusti,Antonio Anzueto,B. Berg,A. S. Buist,Peter M.A. Calverley,Niels H. Chavannes,T. Dillard,Bonnie F. Fahy,Alan M. Fein,John E. Heffner,Suzanne C. Lareau,Paula Meek,Fernando J. Martinez,Walter T. McNicholas,Jean W M Muris,E. Austegard,Romain Pauwels,S. I. Rennard,Adriano G. Rossi,NM Siafakas,B. Tiep,Jørgen Vestbo,E. F. M. Wouters,Richard ZuWallack +25 more
TL;DR: The main goals of the updated document are to improve the quality of care provided to patients with COPD and to develop the project using a disease-oriented approach.
Book
Chronic obstructive pulmonary disease
TL;DR: The most important bacterial causes of exacerbations of COPD are nontypeable Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pneumoniae and Chlamydia pneumoniae.
Journal ArticleDOI
Global initiative for chronic obstructive lung disease.
Lynn B. Gerald,William C. Bailey +1 more
TL;DR: Representatives from many countries serve as a network for the dissemination and implementation of programs for diagnosis, management, and prevention of COPD.
References
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Random-effects models for longitudinal data
Nan M. Laird,James H. Ware +1 more
TL;DR: In this article, a unified approach to fitting two-stage random-effects models, based on a combination of empirical Bayes and maximum likelihood estimation of model parameters and using the EM algorithm, is discussed.
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Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
Journal ArticleDOI
Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1: The Lung Health Study
Nicholas R. Anthonisen,John E. Connett,James P. Kiley,Murray D. Altose,William C. Bailey,A. Sonia Buist,William A. Conway,Paul L. Enright,Richard E. Kanner,Peggy O'Hara,Gregory R. Owens,Paul D. Scanlon,Donald P. Tashkin,Robert A. Wise,M. D. Altose,Alfred F Connors,Susan Redline,C. Deitz,R. F. Rakos,W. A. Conway,A. Dehorn,J. C. Ward,C. S. Hoppe Ryan,R. L. Jentons,J. A. Reddick,C. Sawicki,R. A. Wise,S. Permutt,Cynthia S. Rand,P. D. Scanlon,L. J. Davis,R. D. Hurt,R. D. Miller,D. E. Williams,G. M. Caron,G. G. Lauger,S. M. Toogood,A. S. Buist,W. M. Bjornson,L. R. Johnson,W. C. Bailey,C. M. Brooks,J. J. Dolce,D. M. Higgins,M. A. Johnson,C. D. Lorish,B. A. Martin,D. P. Tashkin,A. H. Coulson,H. Gong,Philip Harber,V. C. Roth,M. Roth,Mitchell A. Nides,M. S. Simmons,I. Zuniga,N. R. Anthonisen,J. Manfreda,R. P. Murray,S. C. Rempel Rossum,J. M. Stoyko,J. E. Connett,M. O. Kjelsberg,M. K. Cowles,D. A. Durkin,P. L. Enright,K. J. Kurnow,W. W. Lee,P. G. Lindgren,S. J. Mongin,P. O'hara,H. T. Voelker,Lance A. Waller,G. R. Owens,R. M. Rogers,J. J. Johnston,F. P. Pope,F. M. Vitale,R. E. Kanner,M. A. Rigdon,K. C. Benton,P. M. Grant,M. Becklake,Benjamin Burrows,P. Cleary,P. Kimbel,L. Nett,J. K. Ockene,R. M. Senior,G. L. Snider,W. Spitzer,O. D. Williams,S. S. Hurd,J. P. Kiley,M. C. Ayres,S. M. Ayres,R. E. Hyatt,Benjamin A. Mason +97 more
TL;DR: An aggressive smoking intervention program significantly reduces the age-related decline in FEV 1 in middle-aged smokers with mild airways obstruction and use of an inhaled anticholinergic bronchodilator results in a relatively small improvement inFEV 1 that appears to be reversed after the drug is discontinued.
Journal ArticleDOI
Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma.
Tari Haahtela,Markku Järvinen,Tuomo Kava,Kirsti Kiviranta,Sirkka Koskinen,Kaarina Lehtonen,Kurt Nikander,Tore Persson,Kaija Reinikainen,Olof Selroos,Anssi Sovijärvi,Brita Stenius-Aarniala,Thore Svahn,Ritva Tammivaara,Lauri A. Laitinen +14 more
TL;DR: Antiinflammatory therapy with inhaled budesonide is an effective first-line treatment for patients with newly detected, mild asthma, and it is superior to the use of terbutaline in such patients.
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