Journal ArticleDOI
Long-Term Marathon Running Is Associated with Low Coronary Plaque Formation in Women.
William O. Roberts,Robert S. Schwartz,Stacia Merkel Kraus,Jonathan G. Schwartz,Gretchen Peichel,Ross Garberich,John R. Lesser,Stephen N Oesterle,Kelly Wickstrom,Thomas Knickelbine,Kevin M. Harris +10 more
TLDR
Developing coronary artery plaque in long-term women marathon runners appears related to older age and more cardiac risk factors, although the runners with coronary plaque had accumulated significantly more years running marathons.Abstract:
IntroductionMarathon running is presumed to improve cardiovascular risk, but health benefits of high volume running are unknown. High-resolution coronary computed tomography angiography and cardiac risk factor assessment were completed in women with long-term marathon running histories to coread more
Citations
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Journal ArticleDOI
Prevalence of Subclinical Coronary Artery Disease in Masters Endurance Athletes With a Low Atherosclerotic Risk Profile
Ahmed Merghani,Viviana Maestrini,Viviana Maestrini,Stefania Rosmini,Andrew T Cox,Harshil Dhutia,Rachel Bastiaenan,Sarojini David,Tee Joo Yeo,Rajay Narain,Aneil Malhotra,Michael Papadakis,Mathew G Wilson,Maite Tome,Khaled Alfakih,James C. Moon,Sanjay Sharma +16 more
TL;DR: Most lifelong masters endurance athletes with a low atherosclerotic risk profile have normal CAC scores, and male athletes are more likely to have a CAC score >300 Agatston units or coronary plaques compared with sedentary males with a similar risk profile.
Journal ArticleDOI
Exercise-Related Acute Cardiovascular Events and Potential Deleterious Adaptations Following Long-Term Exercise Training: Placing the Risks Into Perspective–An Update: A Scientific Statement From the American Heart Association
Barry A. Franklin,Paul D. Thompson,Salah S. Al-Zaiti,Christine M. Albert,Marie-France Hivert,Benjamin D. Levine,Felipe Lobelo,Kushal Madan,Anjail Z Sharrief,Thijs M. H. Eijsvogels +9 more
TL;DR: The goal is to provide healthcare professionals with updated information to advise patients on appropriate preparticipation screening and the benefits and risks of physical activity or physical exertion in varied environments and during competitive events.
Journal ArticleDOI
Association of All-Cause and Cardiovascular Mortality With High Levels of Physical Activity and Concurrent Coronary Artery Calcification
Laura F. DeFina,Nina B. Radford,Carolyn E. Barlow,Benjamin L. Willis,David Leonard,William L. Haskell,Stephen W. Farrell,Andjelka Pavlovic,Katelyn Abel,Jarett D. Berry,Amit Khera,Benjamin D. Levine,Benjamin D. Levine +12 more
TL;DR: There is evidence that high levels of physical activity (≥3000 MET-min/wk) are associated with prevalent CAC but are not associated with increased all-cause or CVD mortality after a decade of follow-up, even in the presence of clinically significant CAC levels.
Journal ArticleDOI
Exercise and Coronary Atherosclerosis Observations, Explanations, Relevance, and Clinical Management
Vincent L. Aengevaeren,Arend Mosterd,Sanjay Sharma,Niek H J Prakken,Stefan Möhlenkamp,Paul D. Thompson,Birgitta K. Velthuis,Thijs M. H. Eijsvogels +7 more
TL;DR: A review of the medical literature demonstrates that the prevalence of coronary artery calcification and atherosclerotic plaques, which are strong predictors for future cardiovascular morbidity and mortality, was higher in athletes compared with controls, and wasHigher in the most active athletes comparedwith less active athletes.
Journal ArticleDOI
The female advantage in cardiovascular disease: Do vascular beds contribute equally?
TL;DR: The authors conclude that the gender difference in atherosclerosis is larger in the coronary vessels than in other vascular beds, and is absent in the aorta and the lower-extremity vessels.
References
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Journal ArticleDOI
Cardiac arrest during long-distance running races.
Jonathan H. Kim,Rajeev Malhotra,George Chiampas,Chris Troyanos,John C. Cianca,Rex Neal Smith,Thomas J. Wang,William O. Roberts,Paul D. Thompson,Aaron L. Baggish +9 more
TL;DR: Marathons and half-marathons are associated with a low overall risk of cardiac arrest and sudden death, and initiation of bystander-administered cardiopulmonary resuscitation and an underlying diagnosis other than hypertrophic cardiomyopathy were the strongest predictors of survival.
Journal ArticleDOI
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Stefan Möhlenkamp,Nils Lehmann,Frank Breuckmann,Martina Bröcker-Preuss,Kai Nassenstein,Martin Halle,Thomas Budde,Klaus Mann,Jörg Barkhausen,Gerd Heusch,Karl-Heinz Jöckel,Raimund Erbel +11 more
TL;DR: Conventional cardiovascular risk stratification underestimates the CAC burden in presumably healthy marathon runners, and an increased awareness of a potentially higher than anticipated coronary risk is warranted.
Journal ArticleDOI
Potential Adverse Cardiovascular Effects From Excessive Endurance Exercise
James H. O'Keefe,Harshal Patil,Carl J. Lavie,Anthony Magalski,Robert A. Vogel,Peter A. McCullough +5 more
TL;DR: The hypothesis that long-term excessive endurance exercise may induce adverse CV remodeling warrants further investigation to identify at-risk individuals and formulate physical fitness regimens for conferring optimal CV health and longevity.
Journal ArticleDOI
Risk for sudden cardiac death associated with marathon running
TL;DR: The low risk for sudden death identified in long-distance runners from the general population suggests that routine screening for cardiovascular disease in such athletic populations may not be justifiable.
Journal ArticleDOI
Acute cardiac effects of marathon running.
Justin E. Trivax,Barry A. Franklin,James A. Goldstein,Kavitha Chinnaiyan,Michael Gallagher,Adam deJong,James M. Colar,David E. Haines,Peter A. McCullough +8 more
TL;DR: Marathon running causes dilation of the right atrium and right ventricle, reduction of right ventricular ejection fraction, and release of cardiac troponin I and B-type natriuretic peptide but does not appear to result in ischemic injury to any chamber.