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Isabella Kardys
Researcher at Erasmus University Rotterdam
Publications - 214
Citations - 5508
Isabella Kardys is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 31, co-authored 163 publications receiving 4418 citations. Previous affiliations of Isabella Kardys include Erasmus University Medical Center.
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Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
G. Eiriksdottir,T. B. Harris,L. J. Launer,Vilmundur Gudnason,Aaron R. Folsom,Gavin Andrews,C. M. Ballantyne,Nilesh J. Samani,A. S. Hall,P. S. Braund,A. J. Balmforth,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,Gordon D.O. Lowe,Nicholas J. Timpson,Shah Ebrahim,Yoav Ben-Shlomo,George Davey-Smith,Børge G. Nordestgaard,Anne Tybjærg-Hansen,Jeppe Zacho,Matthew A. Brown,Manjinder S. Sandhu,Sally L. Ricketts,Sofie Ashford,Leslie A. Lange,Alexander P. Reiner,Mary Cushman,Russel Tracy,C. Wu,J. Ge,Y. Zou,A. Sun,Joseph Hung,Brendan McQuillan,Peter L. Thompson,John Beilby,Nicole M. Warrington,Lyle J. Palmer,Christoph Wanner,Christiane Drechsler,Michael Hoffmann,F. G. R. Fowkes,Ioanna Tzoulaki,Meena Kumari,Michelle A. Miller,Michael Marmot,Charlotte Onland-Moret,Y. T. van der Schouw,J.M.A. Boer,Cisca Wijmenga,Kay-Tee Khaw,Ramachandran S. Vasan,Renate B. Schnabel,J. F. Yamamoto,E J Benjamin,Heribert Schunkert,Jeanette Erdmann,Inke R. König,Christian Hengstenberg,Benedetta D. Chiodini,MariaGrazia Franzosi,Silvia Pietri,Francesca Gori,Megan E. Rudock,Yongmei Liu,Kurt Lohman,Steve E. Humphries,Anders Hamsten,Paul Norman,Graeme J. Hankey,Konrad Jamrozik,Eric B. Rimm,J. K. Pai,Bruce M. Psaty,Susan R. Heckbert,J. C. Bis,Salim Yusuf,Sonia S. Anand,Engert Jc,C. Xie,Ryan L. Collins,Robert Clarke,David L.H. Bennett,Jaspal S. Kooner,John C. Chambers,Paul Elliott,W. März,Marcus E. Kleber,Bernhard O. Böhm,Winkelmann Br,Olle Melander,Göran Berglund,Wolfgang Koenig,Barbara Thorand,Jens Baumert,Annette Peters,JoAnn E. Manson,J.A. Cooper,P.J. Talmud,Per Ladenvall,Lovisa Johansson,J. H. Jansson,Göran Hallmans,Muredach P. Reilly,Liming Qu,Man Li,Daniel J. Rader,Hugh Watkins,Jemma C. Hopewell,Danish Saleheen,John Danesh,Philippe M. Frossard,Naveed Sattar,Michele Robertson,J. Shepherd,Ernst J. Schaefer,A. Hofman,J. C. M. Witteman,Isabella Kardys,Abbas Dehghan,U de Faire,Anna M. Bennet,Bruna Gigante,Karin Leander,Bas J M Peters,A.H. Maitland-van der Zee,A.H. De Boer,Olaf H. Klungel,Philip Greenland,J. Dai,Simin Liu,Eric J. Brunner,Mika Kivimäki,Denis St. J. O’Reilly,Ian Ford,Chris J. Packard +137 more
TL;DR: Human genetic data indicate that C reactive protein concentration itself is unlikely to be even a modest causal factor in coronary heart disease.
Journal ArticleDOI
Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration.
Dominiek D. G. Despriet,Caroline C W Klaver,Jacqueline C.M. Witteman,Arthur A.B. Bergen,Isabella Kardys,Moniek P.M. de Maat,Sharmila S. Boekhoorn,Johannes R. Vingerling,Albert Hofman,Ben A. Oostra,André G. Uitterlinden,Theo Stijnen,Cornelia M. van Duijn,Paulus T. V. M. de Jong +13 more
TL;DR: The Rotterdam Study as discussed by the authors found that CFH Y402H polymorphism may account for a substantial proportion of AMD in individuals similar to those in the Rotterdean Study and may confer particular risk in the presence of environmental and genetic stimulators of complement cascade.
Journal ArticleDOI
In vivo detection of high-risk coronary plaques by radiofrequency intravascular ultrasound and cardiovascular outcome: results of the ATHEROREMO-IVUS study.
Jin M. Cheng,Hector M. Garcia-Garcia,Sanneke P.M. de Boer,Isabella Kardys,Jung Ho Heo,K. Martijn Akkerhuis,Rohit M. Oemrawsingh,Ron T. van Domburg,Jurgen Ligthart,Karen Witberg,Evelyn Regar,Patrick W. Serruys,Robert-Jan van Geuns,Eric Boersma +13 more
TL;DR: In patients undergoing coronary angiography, the presence of IVUS virtual histology-derived TCFA lesions in a non-culprit coronary artery is strongly and independently predictive for the occurrence of MACE within 1 year, particularly of death and ACS.
Journal ArticleDOI
Spatial QRS-T angle predicts cardiac death in a general population
Isabella Kardys,Jan A. Kors,Irene M. van der Meer,Albert Hofman,Deirdre A. M. van der Kuip,Jacqueline C.M. Witteman +5 more
TL;DR: The spatial QRS-T angle is a strong and independent predictor of cardiac mortality in the elderly and stronger than any of the classical cardiovascular risk factors and ECG risk indicators and provides additional value to them in predicting fatal cardiac events.
Journal ArticleDOI
Genetic Variation, C-Reactive Protein Levels, and Incidence of Diabetes
Abbas Dehghan,Isabella Kardys,Moniek P.M. de Maat,André G. Uitterlinden,Eric J.G. Sijbrands,Aart H. Bootsma,Theo Stijnen,Albert Hofman,Miranda T. Schram,Jacqueline C.M. Witteman +9 more
TL;DR: The hypothesis that serum CRP enhances the development of diabetes is supported, as the most common genetic haplotype was associated with a significantly lower CRP level compared with the three other haplotypes.