Journal ArticleDOI
Male age negatively impacts embryo development and reproductive outcome in donor oocyte assisted reproductive technology cycles.
John L. Frattarelli,Kathleen A. Miller,Bradley T Miller,Karen E. Elkind-Hirsch,Richard T. Scott +4 more
TLDR
After controlling for female age with use of the donor oocyte model, male age >50 years significantly affected pregnancy outcomes and blastocyst formation rates.About:
This article is published in Fertility and Sterility.The article was published on 2008-07-01. It has received 176 citations till now. The article focuses on the topics: In vitro fertilisation & Embryo transfer.read more
Citations
More filters
Journal ArticleDOI
Demographic and medical consequences of the postponement of parenthood
TL;DR: In general, women have partners who are several years older than themselves and it is important to focus more on the combined effect of higher female and male age on infertility and reproductive outcome.
Journal ArticleDOI
Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring
TL;DR: An exhaustive literature review has demonstrated negative effects on sperm quality and testicular functions with increasing paternal age, and the need to educate infertile couples on the disturbing links between increased paternal age and rising disorders in their offspring.
Journal ArticleDOI
Consistent age-dependent declines in human semen quality: A systematic review and meta-analysis
TL;DR: It is suggested that greater focus on collection of DNA fragmentation and progressive motility in a clinical setting may lead to better patient outcomes during fertility treatments of aging couples, even though sperm concentration did not decline with increasing male age.
Journal ArticleDOI
Advanced Reproductive Age and Fertility
Kimberly E. Liu,Allison Case,Anthony Cheung,Sony Sierra,Saleh AlAsiri,Belina Carranza-Mamane,Cathie Dwyer,James Graham,Jon Havelock,Robert Hemmings,Francis Lee,Ward Murdock,Vyta Senikas,Tannys D.R. Vause,Benjamin Chee-Man Wong +14 more
TL;DR: This guideline reviews options for the assessment of ovarian reserve and fertility treatments using ART with women of advanced reproductive age presenting with infertility and improves awareness of the natural age-related decline in female and male fertility.
Journal ArticleDOI
Delayed childbearing: effects on fertility and the outcome of pregnancy.
Juan Balasch,Eduard Gratacós +1 more
TL;DR: The impact of delaying childbearing from a public health perspective cannot be overestimated and should be in the agenda of public health policies for the years to come.
References
More filters
Journal ArticleDOI
Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities*
TL;DR: It is demonstrated that, in morphologically and developmentally normal human embryos, cleavage-stage aneuploidy significantly increases with maternal age, and the results suggest that implantation failure in older women largely could be due to aneuPLoidy.
Journal ArticleDOI
Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities**Presented at the 50th Annual Meeting of The American Fertility Society, San Antonio, Texas, November 4 to 9, 1994, where it was awarded the prize paper of the Society for Assisted Reproductive Technology.
TL;DR: It is demonstrated that, in morphologically and developmentally normal human embryos, cleavage-stage aneuploidy significantly increases with maternal age, and the results suggest that implantation failure in older women largely could be due to aneuPLoidy.
Journal ArticleDOI
Effects of male age on semen quality and fertility: a review of the literature
TL;DR: The weight of the evidence suggests that increased male age is associated with a decline in semen volume, sperm motility, and sperm morphology but not with sperm concentration.
Journal ArticleDOI
Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women.
TL;DR: The data suggest that the regulatory mechanisms responsible for assembly of the meiotic spindle are significantly altered in older women, leading to the high prevalence of aneuploidy.
Journal ArticleDOI
Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility.
Daniel Navot,R.A. Bergh,M.A. Williams,G.J. Garrisi,Ida Guzman,Benjamin Sandler,Lawrence Grunfeld +6 more
TL;DR: The data suggest that the age-related decline in female fertility is attributable to oocyte quality and is correctable by ovum donation, and the uterus can adequately sustain pregnancies even when reproductive potential is artificially prolonged into the late 40s.