scispace - formally typeset
Open AccessJournal ArticleDOI

Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation.

Christopher S. Kovacs, +1 more
- 01 Dec 1997 - 
- Vol. 18, Iss: 6, pp 832-872
Reads0
Chats0
TLDR
Maternal adaptive goals during pregnancy and during lactation, andfetal response to maternal hyper- or hypoparathy-roidism, and Integrated fetal calcium homeostasis, are studied.
Abstract
I. Introduction II. Maternal Physiology and Pathophysiology During Pregnancy A. Maternal adaptive goals during pregnancy B. Mineral ions and calcitropic hormones C. Intestinal absorption of calcium D. Renal handling of calcium E. Skeletal calcium metabolism F. Primary hyperparathyroidism G. Hypoparathyroidism and pseudohypopara- thyroidism H. Summary III. Fetal-Placental Physiology and Pathophysiology A. Fetal adaptive goals B. Mineral ions and calcitropic hormones C. Fetal-placental calcium transport D. Renal handling of calcium and the amniotic fluid E. Skeletal calcium metabolism F. Fetal response to maternal hyper- or hypoparathy-roidism G. Integrated fetal calcium homeostasis H. Summary IV. Maternal Physiology and Pathophysiology During Lactation A. Maternal adaptive goals during lactation B. Mineral ions and calcitropic hormones C. Intestinal absorption of calcium D. Renal handling of calcium E. Skeletal calcium metabolism F. Hypoparathyroidism and pseudohypoparathy- roidism G. Summary V. Neonatal P...

read more

Content maybe subject to copyright    Report

Citations
More filters
Journal ArticleDOI

Vitamin D for Health: A Global Perspective

TL;DR: There is potentially a great upside to increasing the vitamin D status of children and adults worldwide for improving musculoskeletal health and reducing the risk of chronic illnesses, including some cancers, autoimmune diseases, infectious diseases, type 2 diabetes mellitus, neurocognitive disorders and mortality.
Journal ArticleDOI

The serum protein α2–Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification

TL;DR: A critical role is demonstrated of the serum protein alpha2-Heremans-Schmid glycoprotein (Ahsg) as an inhibitor of unwanted mineralization and a novel therapeutic concept to prevent ectopic calcification accompanying various diseases is provided.
Journal ArticleDOI

RANK-L and RANK: T Cells, Bone Loss, and Mammalian Evolution

TL;DR: Modulation of these systems provides a unique opportunity to design novel therapeutics to inhibit bone loss in arthritis, periodontal disease, and osteoporosis.
Journal ArticleDOI

The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development

TL;DR: It is reported that mice lacking OPGL or its receptor RANK fail to form lobulo-alveolar mammary structures during pregnancy, resulting in death of newborns and a novel paradigm in mammary gland development and an evolutionary rationale for hormonal regulation and gender bias of osteoporosis in females.
Journal ArticleDOI

Breastfeeding and maternal health outcomes: a systematic review and meta-analysis

TL;DR: A systematic literature search was conducted in PubMed Cochrane Library and CABI databases to evaluate the effect of breastfeeding on longterm (breast carcinoma ovarian carcinoma osteoporosis and type 2 diabetes mellitus) and short-term (lactational amenorrhoea post-partum depression postpartum weight change) maternal health outcomes.
References
More filters

A longitudinal study

TL;DR: A longitudinal study of service delivery within MRI services at Auckland University for patients, researchers and referring practitioners has been carried out since 2006 as mentioned in this paper, with a focus on the effects of service provision on patient satisfaction.
Journal ArticleDOI

A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression

TL;DR: The isolation of full-length complementary DNA clones of a putative hypercalcemia factor, and the expression from the cloned DNA of the active protein in mammalian cells that has significant homology with parathyroid hormone in the amino-terminal region are reported.
Journal ArticleDOI

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.

TL;DR: Analysis of earlier developmental stages revealed that disturbance in cartilage growth preceded abnormal endochondral bone formation, and direct evidence implicating PTHrP in normal skeletal development is provided to emphasize its potential involvement in human osteochondrodysplasias.
Related Papers (5)