Metapneumovirus and acute wheezing in children
Tuomas Jartti,Bernadette G. van den Hoogen,Roberto P. Garofalo,Albert D. M. E. Osterhaus,Olli Ruuskanen +4 more
TLDR
Human metapneumovirus is a clinically important causative agent of acute wheezing in young children and regulated upon activation.About:
This article is published in The Lancet.The article was published on 2002-11-02 and is currently open access. It has received 278 citations till now. The article focuses on the topics: Human metapneumovirus & Respiratory virus.read more
Citations
More filters
Journal ArticleDOI
Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children.
John V. Williams,Paul A. Harris,Sharon J. Tollefson,Lisa L. Halburnt-Rush,Joyce M. Pingsterhaus,Kathryn M. Edwards,Peter F. Wright,James E. Crowe +7 more
TL;DR: Human metapneumovirus infection is a leading cause of respiratory tract infection in the first years of life, with a spectrum of disease similar to that of respiratory syncytial virus.
Journal ArticleDOI
Epidemiology and Clinical Characteristics of Community-Acquired Pneumonia in Hospitalized Children
Ian C. Michelow,Kurt Olsen,Juanita Lozano,Nancy K. Rollins,Lynn B. Duffy,Thedi Ziegler,Jaana Kauppila,Maija Leinonen,George H. McCracken +8 more
TL;DR: The data confirm the importance of S pneumoniae and the frequent occurrence of bacterial and viral coinfections in children with pneumonia and will facilitate age-appropriate antibiotic selection and future evaluation of the clinical effectiveness of the pneumococcal conjugate vaccine as well as other candidate vaccines.
Journal ArticleDOI
Human metapneumovirus infections in hospitalized children.
Guy Boivin,Gaston De Serres,Stéphanie Côté,Rodica Gilca,Yacine Abed,Louis Rochette,Michel G. Bergeron,Pierre Déry +7 more
TL;DR: HMPV is an important cause of illness in young children with a similar, although less severe, clinical presentation to that of HRSV.
Journal ArticleDOI
Prevalence and Clinical Symptoms of Human Metapneumovirus Infection in Hospitalized Patients
Bernadette G. van den Hoogen,Gerard J. J. van Doornum,John C. Fockens,Jan J. Cornelissen,Walter E.P. Beyer,Ronald de Groot,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +7 more
TL;DR: In this article, the authors performed a 17-month period analysis of the prevalence of and clinical symptoms associated with human metapneumovirus (hMPV) infection, among patients in a university hospital in The Netherlands.
Journal ArticleDOI
Children with respiratory disease associated with metapneumovirus in Hong Kong.
J. S. Malik Peiris,Wing Hong Tang,Kwok-Hung Chan,Pek-Lan Khong,Yi Guan,Yu-Lung Lau,Susan S. Chiu +6 more
TL;DR: Human metapneumovirus (HMPV) is a newly discovered pathogen thought to be associated with respiratory disease and was associated with clinical diagnoses of pneumonia, asthma exacerbation, or acute bronchiolitis over a 13-month period in Hong Kong.
References
More filters
Journal ArticleDOI
A newly discovered human pneumovirus isolated from young children with respiratory tract disease.
Bernadette G. van den Hoogen,Jan C. de Jong,Jan Groen,Thijs Kuiken,Ronald de Groot,Ron A. M. Fouchier,Albert D. M. E. Osterhaus +6 more
TL;DR: Serological studies showed that by the age of five years, virtually all children in the Netherlands have been exposed to human metapneumovirus and that the virus has been circulating in humans for at least 50 years.
Journal ArticleDOI
Viruses and Bacteria in the Etiology of the Common Cold
Mika J. Mäkelä,Tuomo Puhakka,Olli Ruuskanen,Maija Leinonen,Pekka Saikku,Marko Kimpimäki,Soile Blomqvist,Timo Hyypiä,P. Arstila +8 more
TL;DR: The results show that although approximately 50% of episodes of the common cold were caused by rhinoviruses, the etiology can vary depending on the epidemiological situation with regard to circulating viruses.
Journal ArticleDOI
Characterization of Human Metapneumoviruses Isolated from Patients in North America
Teresa C. T. Peret,Guy Boivin,Yan Li,Michel Couillard,Charles D. Humphrey,Albert D. M. E. Osterhaus,Dean D. Erdman,Larry J. Anderson +7 more
TL;DR: Sequence studies of the nucleocapsid, fusion, and polymerase genes identified 2 main lineages of HMPV and cocirculation of both lineages during the same year.
Journal ArticleDOI
Respiratory Syncytial Virus Induces Selective Production of the Chemokine RANTES by Upper Airway Epithelial Cells
Tadahito Saito,Ronald W. Deskin,Antonella Casola,Helene A. Haeberle,Barbara Olszewska,Peter B. Ernst,Rafeul Alam,Pearay L. Ogra,Roberto P. Garofalo +8 more
TL;DR: RANTES (regulated upon activation, normal T cell-expressed and -secreted), which was present in negligible concentrations in uninfected cultures, was strongly induced by RSV infection, in a dose- and time-dependent manner.