Journal ArticleDOI
Microwave-promoted three-component coupling of aldehyde, alkyne, and amine via C-H activation catalyzed by copper in water.
TLDR
The preliminary experiment using (S)-proline methyl ester as a chiral source demonstrated that it could be developed to be a direct and highly diastereoselective method for construction of chiral propargylamines.About:
This article is published in Organic Letters.The article was published on 2004-02-24. It has received 262 citations till now. The article focuses on the topics: A3 coupling reaction & Alkyne.read more
Citations
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Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
TL;DR: Reaction of R,â-Unsaturated Carbonyl Compounds 3127: Reaction of R-UnSaturated Carbonies 3127 7.1.6.
Journal ArticleDOI
Asymmetric multicomponent reactions (amcrs): the new frontier
Diego J. Ramón,Miguel Yus +1 more
TL;DR: Asymmetric multicomponent reactions involve the preparation of chiral compounds by the reaction of three or more reagents added simultaneously and has some advantages over classic divergent reaction strategies, such as lower costs, time, and energy, as well as environmentally friendlier aspects.
Journal ArticleDOI
Alternative synthetic methods through new developments in catalysis by gold.
TL;DR: The results show clear trends in gold-Catalyzed C-H Bond Functionalization and Selective Reductions, and catalytic Hydrogenation of Alkenes and 1,3-Dienes, as well as in other areas of science.
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Microwave-Assisted Synthesis in Water as Solvent
Doris Dallinger,C. Oliver Kappe +1 more
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Reactions of C−H Bonds in Water
References
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Journal ArticleDOI
Organic reactions in aqueous media - with a focus on carbon-carbon bond formation
TL;DR: In the last decade, there has been increasing recognition that organic reactions carried out in aqueous media may offer advantages over those occurring in organic solvents as discussed by the authors, which is the essence of organic synthesis.
Journal ArticleDOI
Additions of Organometallic Reagents to C=N Bonds: Reactivity and Selectivity
Journal ArticleDOI
Microwave-accelerated homogeneous catalysis in organic chemistry.
TL;DR: This specific account mainly summarizes the own experiences in developing rapid, robust, and selective microwave-assisted transition metal-catalyzed homogeneous reactions, which will be of importance in the search for green laboratory-scale synthesis.
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A highly efficient three-component coupling of aldehyde, alkyne, and amines via C-H activation catalyzed by gold in water
Chunmei Wei,Chao-Jun Li +1 more