Journal ArticleDOI
Mobilization of heavy metals by newer, therapeutically useful chelating agents
H. Vasken Aposhian,R M Maiorino,Diego Gonzalez-Ramirez,Miguel Angel Zúñiga-Charles,Zhao-Fa Xu,Katherine M. Hurlbut,Pablo Junco-Munoz,Richard C. Dart,Mary M. Aposhian +8 more
TLDR
The Dimaval-mercury challenge test holds great promise as a diagnostic test for mercury exposure, especially for low level mercurialism.About:
This article is published in Toxicology.The article was published on 1995-03-31. It has received 255 citations till now. The article focuses on the topics: Dimercaprol.read more
Citations
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Efeito do disseleneto de difenila sobre a toxicidade induzida por cloreto de mercúrio em camundongos
TL;DR: The results showed that the concomitant and acute exposure to HgCl2 and therapeutic agents tested presented toxic effects, and that the preventive therapy with diphenyl diselenide (PhSe)2 was effective in protecting against immunological and hematological alterations induced by subchronic HGCl2 exposure.
Journal ArticleDOI
On the interaction of vanadium species with the monoisoamyl ester of meso-2,3-dimercaptosuccinic acid.
TL;DR: The results of this study suggest that MiADMSA might be a potentially useful detoxification agent for vanadium.
Journal ArticleDOI
Adverse drug reactions to poison antidotes: Part 2
TL;DR: Administration of antidotes in cyanide poisoning or dimercaprol in arsenic poisoning carries a high risk of adverse reactions, and the clinical decision to use the antidote is only taken in severe poisoning.
Journal ArticleDOI
2,3-Dimercaptopropanol, 2,3-dimercaptopropane-1-sulfonic acid and meso-2,3-dimercaptosuccinic acid acute administration diferentially change biochemical parameters in mice.
TL;DR: Clinical reliance on DMSA, an orally administered chelating, has expanded greatly during the last years particularly after its approval for the clinical use against childhood lead poisoning by US Food and Drug Administration (FDA) (Jorgensen 1993).
References
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Book
The pharmacological basis of therapeutics
TL;DR: In this article, 42 authors share the herculean task of reviewing the flood of recent literature on pharmacology and rational use of drugs, under single or dual authorship they contribute the 76 chapters in the 18 sections.
BookDOI
Biological monitoring of toxic metals.
TL;DR: An overview of several important aspects of biological monitoring is given, which can be used to identify individuals, or groups of individuals, with high exposure or at high risk.
Journal ArticleDOI
Dmsa and dmps-water soluble antidotes for heavy metal poisoning
TL;DR: This article reviews the pharmacological properties and the uses of two important antidotes for heavy metal poisoning, DMSA and DMPS, water soluble chemical analogs of dimercaprol, which have less toxicity, greater water solubility, and lim ited lipid solubilities, and are effective when given orally.