Journal ArticleDOI
Mobilization of heavy metals by newer, therapeutically useful chelating agents
H. Vasken Aposhian,R M Maiorino,Diego Gonzalez-Ramirez,Miguel Angel Zúñiga-Charles,Zhao-Fa Xu,Katherine M. Hurlbut,Pablo Junco-Munoz,Richard C. Dart,Mary M. Aposhian +8 more
TLDR
The Dimaval-mercury challenge test holds great promise as a diagnostic test for mercury exposure, especially for low level mercurialism.About:
This article is published in Toxicology.The article was published on 1995-03-31. It has received 255 citations till now. The article focuses on the topics: Dimercaprol.read more
Citations
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Journal ArticleDOI
The effects of meso-2,3-dimercaptosuccinic acid and oligomeric procyanidins on acute lead neurotoxicity in rat hippocampus
TL;DR: It was proved that reactive oxygen species and oxidative damage were implicated in the induction of apoptosis induced by lead in the hippocampus and a reasonable deduction can be made that the complex of OPC-Pb(2+) prevents or at least weakens the neurotoxicity of Pb( 2+).
Journal ArticleDOI
Sodium 2,3-dimercapto-1-propanesulfonate (DMPS) treatment does not redistribute lead or mercury to the brain of rats
TL;DR: The results of these experiments demonstrated that lead or mercuric ions were not redistributed to or increased in the brains of rats during the initial days of DMPS treatment.
Journal ArticleDOI
Beryllium-induced toxicity and its prevention by treatment with chelating agents.
TL;DR: Tiron was found to be significantly more effective than CaNa2EDTA in reducing the beryllium concentration in the liver, kidney and lungs, and these findings were further confirmed by atomic adsorption spectrophotometry.
Journal ArticleDOI
gamma-Gliadin: a presumptive allergen causing wheat-dependent exercise-induced anaphylaxis.
TL;DR: The erbium:YAG laser was found to be a suitable tool for effective removal of the spines from sea-urchin spinous injury patients and no delayed granulomatous foreign-body reactions or other complications have been observed during 1 year of follow-up.
Journal ArticleDOI
MRP2 involvement in renal proximal tubular elimination of methylmercury mediated by DMPS or DMSA.
TL;DR: Findings indicate that MRP2 does play a role in DMPS- and DMSA-mediated elimination of mercury from the kidney and in inside-out membrane vesicles prepared from hMRP2-transfected Sf9 cells show that uptake of DMPS andDMSA S-conjugates of CH(3)Hg(+) was greater in the vesicle containing hMRp2 than in control ves Balls.
References
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Book
The pharmacological basis of therapeutics
TL;DR: In this article, 42 authors share the herculean task of reviewing the flood of recent literature on pharmacology and rational use of drugs, under single or dual authorship they contribute the 76 chapters in the 18 sections.
BookDOI
Biological monitoring of toxic metals.
TL;DR: An overview of several important aspects of biological monitoring is given, which can be used to identify individuals, or groups of individuals, with high exposure or at high risk.
Journal ArticleDOI
Dmsa and dmps-water soluble antidotes for heavy metal poisoning
TL;DR: This article reviews the pharmacological properties and the uses of two important antidotes for heavy metal poisoning, DMSA and DMPS, water soluble chemical analogs of dimercaprol, which have less toxicity, greater water solubility, and lim ited lipid solubilities, and are effective when given orally.