Journal ArticleDOI
Mobilization of heavy metals by newer, therapeutically useful chelating agents
H. Vasken Aposhian,R M Maiorino,Diego Gonzalez-Ramirez,Miguel Angel Zúñiga-Charles,Zhao-Fa Xu,Katherine M. Hurlbut,Pablo Junco-Munoz,Richard C. Dart,Mary M. Aposhian +8 more
TLDR
The Dimaval-mercury challenge test holds great promise as a diagnostic test for mercury exposure, especially for low level mercurialism.About:
This article is published in Toxicology.The article was published on 1995-03-31. It has received 255 citations till now. The article focuses on the topics: Dimercaprol.read more
Citations
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Cadmium inhibits δ-aminolevulinate dehydratase from rat lung in vitro: Interaction with chelating and antioxidant agents
TL;DR: It is demonstrated that Cd(2+)inhibited delta-ALA-D activity and chelating and antioxidant agents, alone or combined, did not restore the enzyme activity.
Journal ArticleDOI
Subcutaneous metallic mercury injection for penile augmentation.
TL;DR: The case of a 72-year-old patient who received a subcutaneous injection of metallic mercury into his penis for the purpose of penile aesthetic augmentation is presented, believed to be the first report ofPenile sub cutaneous mercury injection for aesthetic augmented.
Journal Article
Full Reversal of Pb++ Block of L-Type Ca++ Channels Requires Treatment with Heavy Metal Antidotes
TL;DR: The results suggest that Pb++ blocks voltage-gated Ca++ channels by two mechanisms and that full reversal of lead block requires chelator treatment.
Journal ArticleDOI
Zinc chelation reduces traumatic brain injury-induced neurogenesis in the subgranular zone of the hippocampal dentate gyrus.
TL;DR: The present study shows that zinc chelation did not prevent neurodegeneration but did reduce TBI-induced progenitor cell proliferation and neurogenesis, suggesting that zinc has an essential role for modulating hippocampal Neurogenesis after TBI.
Journal ArticleDOI
Integrative medicine and the role of modified citrus pectin/alginates in heavy metal chelation and detoxification--five case reports.
TL;DR: Five case studies presented here show that reduction in toxic heavy metals (74% average decrease) was achieved without side effects, with the use of PectaSol modified citrus pectin (MCP) alone or with an MCP/alginates combination.
References
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Book
The pharmacological basis of therapeutics
TL;DR: In this article, 42 authors share the herculean task of reviewing the flood of recent literature on pharmacology and rational use of drugs, under single or dual authorship they contribute the 76 chapters in the 18 sections.
BookDOI
Biological monitoring of toxic metals.
TL;DR: An overview of several important aspects of biological monitoring is given, which can be used to identify individuals, or groups of individuals, with high exposure or at high risk.
Journal ArticleDOI
Dmsa and dmps-water soluble antidotes for heavy metal poisoning
TL;DR: This article reviews the pharmacological properties and the uses of two important antidotes for heavy metal poisoning, DMSA and DMPS, water soluble chemical analogs of dimercaprol, which have less toxicity, greater water solubility, and lim ited lipid solubilities, and are effective when given orally.