Journal ArticleDOI
Mobilization of heavy metals by newer, therapeutically useful chelating agents
H. Vasken Aposhian,R M Maiorino,Diego Gonzalez-Ramirez,Miguel Angel Zúñiga-Charles,Zhao-Fa Xu,Katherine M. Hurlbut,Pablo Junco-Munoz,Richard C. Dart,Mary M. Aposhian +8 more
TLDR
The Dimaval-mercury challenge test holds great promise as a diagnostic test for mercury exposure, especially for low level mercurialism.About:
This article is published in Toxicology.The article was published on 1995-03-31. It has received 255 citations till now. The article focuses on the topics: Dimercaprol.read more
Citations
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Integrative Medicine and the Role of Modified Citrus Pectin/Alginates in Heavy MetIntegrative Medicine and the Role of Modified Citrus Pectin/Alginates in Heavy Metal Chelation and Detoxification – Five Case Reports
TL;DR: Five case studies presented here show that reduction in toxic heavy metals was achieved without side effects, with the use of PectaSol® modified citrus pectin (MCP) (EcoNugenics) alone or with an MCP/alginates combination.
Journal ArticleDOI
Synthesis and Coordination Chemistry of two N2-donor chelating di(indazolyl)methane ligands: structural characterization and comparison of their metal chelation aptitudes
Claudio Pettinari,Alessandro Marinelli,Fabio Marchetti,Jean Ngoune,Agustín Galindo,Eleuterio Álvarez,Margarita Gómez Gómez +6 more
TL;DR: The N(2)-donor bidentate ligands di(1H-indazol-1-yl)methane (L(1)) and di(2 H-indrazol-2-yl), and their coordination behavior toward Zn(II, Cd(II), and Hg(II) salts has been studied.
Journal ArticleDOI
Chelation in Suspected Prosthetic Hip-Associated Cobalt Toxicity
TL;DR: Interestingly, the authors’ patient presented with liver failure, which has not been described previously in suspected prosthetic hip-associated cobalt toxicity, and NAC appears to be one of the safer and more effective cobalt chelators in an animal model of chronic cobalt poisoning.
Journal ArticleDOI
2,3-Dimercaptopropanol, 2,3-dimercaptopropane-1-sulfonic acid and meso-2,3-dimercaptosuccinic acid increase lead-induced inhibition of δ-aminolevulinate dehydratase in vitro and ex vivo
TL;DR: In fact, BAL and DMPS increase the inhibitory effect of lead on delta-ALA-D activity from mice blood, and the complexes formed were more inhibitory than lead alone in kidney and liver enzyme activity, ex vivo.
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Thermodynamics of the complexation of Hg(II) by cysteinyl peptide ligands using isothermal titration calorimetry
TL;DR: In this article, the authors used isothermal titration calorimetry to better understand the complexation of mercury (II) by cysteine, histidine, tryptophan, and tri-peptides.
References
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Book
The pharmacological basis of therapeutics
TL;DR: In this article, 42 authors share the herculean task of reviewing the flood of recent literature on pharmacology and rational use of drugs, under single or dual authorship they contribute the 76 chapters in the 18 sections.
BookDOI
Biological monitoring of toxic metals.
TL;DR: An overview of several important aspects of biological monitoring is given, which can be used to identify individuals, or groups of individuals, with high exposure or at high risk.
Journal ArticleDOI
Dmsa and dmps-water soluble antidotes for heavy metal poisoning
TL;DR: This article reviews the pharmacological properties and the uses of two important antidotes for heavy metal poisoning, DMSA and DMPS, water soluble chemical analogs of dimercaprol, which have less toxicity, greater water solubility, and lim ited lipid solubilities, and are effective when given orally.