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Journal ArticleDOI

Near-infrared spectroscopy: exposing the dark (venous) side of the circulation.

John P. Scott, +1 more
- 01 Jan 2014 - 
- Vol. 24, Iss: 1, pp 74-88
TLDR
Near‐infrared spectroscopy provides noninvasive continuous access to the venous side of regional circulations that can approximate organ‐specific and global measures to facilitate the detection of circulatory abnormalities and drive goal‐directed interventions to reduce end‐organ ischemic injury.
Abstract
The safety of anesthesia has improved greatly in the past three decades. Standard perioperative monitoring, including pulse oximetry, has practically eliminated unrecognized arterial hypoxia as a cause for perioperative injury. However, most anesthesia-related cardiac arrests in children are now cardiovascular in origin, and standard monitoring is unable to detect many circulatory abnormalities. Near-infrared spectroscopy provides noninvasive continuous access to the venous side of regional circulations that can approximate organ-specific and global measures to facilitate the detection of circulatory abnormalities and drive goal-directed interventions to reduce end-organ ischemic injury.

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Citations
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Journal ArticleDOI

Propofol and thiopental for intravenous induction in neonates: Study protocol for a dose‐finding trial

TL;DR: In this article , a knowledge gap exists concerning the pharmacodynamics of induction doses of propofol and thiopental in neonatal anesthesia, and a limited data about the anesthetic induction dose is available.
Journal ArticleDOI

The Effect of Aminophylline on Urine Output and Fluid Balance after a Single Dose in Children Admitted to the Pediatric Cardiac Intensive Care Unit

TL;DR: Use of aminophylline dosed at 5 mg/kg is safe and leads to improvement in urine output and fluid balance without negatively impacting systemic oxygen delivery or renal filtration function.
Journal ArticleDOI

Association of Immediate Postoperative Hemodynamic and Laboratory Values in Predicting Norwood Admission Outcomes

- 09 Nov 2022 - 
TL;DR: In this article , a single-center retrospective study of infants with functionally univentricular heart admitted to intensive care after the Norwood procedure from January 2011 to January 2020 was conducted.
Journal ArticleDOI

The central nervous system and heart failure.

TL;DR: The purpose of this review is to summarize the changes in the structure and biochemical function of the CNS in patients with chronic heart failure and to discuss their potential importance.
References
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Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

TL;DR: This study randomly assigned patients who arrived at an urban emergency department with severe sepsis or septic shock to receive either six hours of early goal-directed therapy or standard therapy (as a control) before admission to the intensive care unit.
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Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters

TL;DR: Observations by infrared transillumination in the exposed heart and in the brain in cephalo without surgical intervention show that oxygen sufficiency for cytochrome a,a3, function, changes in tissue blood volume, and the average hemoglobin-oxyhemoglobin equilibrium can be recorded effectively and in continuous fashion for research and clinical purposes.
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Reporting and preventing medical mishaps: lessons from non-medical near miss reporting systems

TL;DR: Focusing on data for near misses may add noticeably more value to quality improvement than a sole focus on adverse events, and an environment fostering a rich reporting culture must be created to capture accurate and detailed data about nuances of care.
Journal ArticleDOI

Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock.

TL;DR: Microcirculatory alterations improve rapidly in septic shock survivors but not in patients dying with multiple organ failure, regardless of whether shock has resolved.
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