Journal ArticleDOI
Near-infrared spectroscopy: exposing the dark (venous) side of the circulation.
John P. Scott,George M. Hoffman +1 more
TLDR
Near‐infrared spectroscopy provides noninvasive continuous access to the venous side of regional circulations that can approximate organ‐specific and global measures to facilitate the detection of circulatory abnormalities and drive goal‐directed interventions to reduce end‐organ ischemic injury.Abstract:
The safety of anesthesia has improved greatly in the past three decades. Standard perioperative monitoring, including pulse oximetry, has practically eliminated unrecognized arterial hypoxia as a cause for perioperative injury. However, most anesthesia-related cardiac arrests in children are now cardiovascular in origin, and standard monitoring is unable to detect many circulatory abnormalities. Near-infrared spectroscopy provides noninvasive continuous access to the venous side of regional circulations that can approximate organ-specific and global measures to facilitate the detection of circulatory abnormalities and drive goal-directed interventions to reduce end-organ ischemic injury.read more
Citations
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Journal ArticleDOI
Postoperative Cerebral and Somatic Near-Infrared Spectroscopy Saturations and Outcome in Hypoplastic Left Heart Syndrome
George M. Hoffman,George M. Hoffman,Nancy S. Ghanayem,John P. Scott,John P. Scott,James S. Tweddell,Michael E. Mitchell,Michael E. Mitchell,Kathleen A. Mussatto +8 more
TL;DR: Test the hypothesis that near-infrared spectroscopy (NIRS)-derived cerebral and somatic/renal regional saturations can predict survival by analyzing relationships between standard hemodynamic measures, direct and NIRS measures of saturation, and outcome.
Journal ArticleDOI
Cerebral Oxygenation During Pediatric Cardiac Surgery Using Deep Hypothermia Circulatory Arrest
TL;DR: Brain oxygenation changed at distinct points during surgery in all ages, reflecting fundamental cerebral responses to hypothermic CPB, ischemia, and reperfusion, consistent with experimental work in animals.
Journal ArticleDOI
Sevoflurane anesthesia and brain perfusion
O. Rhondali,Agnès Pouyau,Aurélie Mahr,Simon Juhel,Mathilde De Queiroz,Khalid Rhzioual-Berrada,Sylvain Mathews,Dominique Chassard +7 more
TL;DR: To assess the impact of sevoflurane and anesthesia‐induced hypotension on brain perfusion in children younger than 6 months, a large number of patients were referred to the neonatal intensive care unit.
Journal ArticleDOI
An International, Multicenter, Observational Study of Cerebral Oxygenation during Infant and Neonatal Anesthesia
Vanessa A. Olbrecht,Justin Skowno,Vanessa Marchesini,Lili Ding,Yifei Jiang,Christopher G. Ward,Gaofeng Yu,Huacheng Liu,Bernadette Schurink,Laszlo Vutskits,Jurgen C. de Graaff,Francis X. McGowan,Britta S. von Ungern-Sternberg,C D Kurth,Andrew Davidson +14 more
TL;DR: Mild and moderate low cerebral oxygenation occurred frequently, whereas severe low cerebral saturation was uncommon, and low mean arterial pressure was common and not well associated withLow cerebral saturation.
Journal ArticleDOI
Impact of sevoflurane anesthesia on brain oxygenation in children younger than 2 years.
O. Rhondali,Simon Juhel,Sylvain Mathews,Quentin Cellier,François-Pierrick Desgranges,Aurélie Mahr,Mathilde De Queiroz,Agnès Pouyau,Khalid Rhzioual-Berrada,Dominique Chassard +9 more
TL;DR: To assess the impact of sevoflurane and anesthesia‐induced hypotension on brain oxygenation in children younger than 2 years, a large number of patients were referred to the neonatal intensive care unit.
References
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Journal ArticleDOI
Cerebral Oxygenation During Pediatric Cardiac Surgery Using Deep Hypothermia Circulatory Arrest
TL;DR: Brain oxygenation changed at distinct points during surgery in all ages, reflecting fundamental cerebral responses to hypothermic CPB, ischemia, and reperfusion, consistent with experimental work in animals.
Journal ArticleDOI
Neurodevelopmental Outcomes After Regional Cerebral Perfusion With Neuromonitoring for Neonatal Aortic Arch Reconstruction
Dean B. Andropoulos,Dean B. Andropoulos,R. Blaine Easley,R. Blaine Easley,Kenneth Martin Brady,Kenneth Martin Brady,E. Dean McKenzie,E. Dean McKenzie,Jeffrey S. Heinle,Jeffrey S. Heinle,Heather A. Dickerson,Heather A. Dickerson,Lara S. Shekerdemian,Lara S. Shekerdemian,Marcie Meador,Marcie Meador,Carol Eisenman,Jill V. Hunter,Jill V. Hunter,Marie Turcich,Marie Turcich,Robert G. Voigt,Robert G. Voigt,Charles D. Fraser,Charles D. Fraser +24 more
TL;DR: The neurodevelopmental outcomes in this RCP cohort demonstrate that this technique is effective and safe in supporting the brain during neonatal aortic arch reconstruction, and results in 12-month cognitive outcomes that are at reference population norms.
Journal ArticleDOI
Assessment of the relationship between cerebral and splanchnic oxygen saturations measured by near-infrared spectroscopy and direct measurements of systemic haemodynamic variables and oxygen transport after the Norwood procedure
Jia Li,G Van Arsdell,Gencheng Zhang,Sally Cai,Tilman Humpl,Christopher A. Caldarone,Helen Holtby,A.N. Redington +7 more
TL;DR: Sco2 and Sso2 may reflect the influence of haemodynamic variables and oxygen transport after the Norwood procedure, and the interpretation of NIRS data, in terms of both absolute values and trends, is difficult to rely on clinically.
Journal ArticleDOI
Transcranial cerebral oximetry in random normal subjects
TL;DR: The association of the man regional cerebral hemoglobin oxygen saturation in various groups of individuals with relationship to their age, race, sex and skin color is examined.
Journal ArticleDOI
Regional tissue oxygenation in preterm born infants in association with echocardiographically significant patent ductus arteriosus
TL;DR: The PDA size did not affect cerebral and renal tissue oxygenation, but the mesenteric tissue oxygenations was decreased in infants with a large PDA on NCPAP, and in those with moderate PDA irrespective of the type of respiratory support.
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