Journal ArticleDOI
Near-infrared spectroscopy: exposing the dark (venous) side of the circulation.
John P. Scott,George M. Hoffman +1 more
TLDR
Near‐infrared spectroscopy provides noninvasive continuous access to the venous side of regional circulations that can approximate organ‐specific and global measures to facilitate the detection of circulatory abnormalities and drive goal‐directed interventions to reduce end‐organ ischemic injury.Abstract:
The safety of anesthesia has improved greatly in the past three decades. Standard perioperative monitoring, including pulse oximetry, has practically eliminated unrecognized arterial hypoxia as a cause for perioperative injury. However, most anesthesia-related cardiac arrests in children are now cardiovascular in origin, and standard monitoring is unable to detect many circulatory abnormalities. Near-infrared spectroscopy provides noninvasive continuous access to the venous side of regional circulations that can approximate organ-specific and global measures to facilitate the detection of circulatory abnormalities and drive goal-directed interventions to reduce end-organ ischemic injury.read more
Citations
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Journal ArticleDOI
Postoperative Cerebral and Somatic Near-Infrared Spectroscopy Saturations and Outcome in Hypoplastic Left Heart Syndrome
George M. Hoffman,George M. Hoffman,Nancy S. Ghanayem,John P. Scott,John P. Scott,James S. Tweddell,Michael E. Mitchell,Michael E. Mitchell,Kathleen A. Mussatto +8 more
TL;DR: Test the hypothesis that near-infrared spectroscopy (NIRS)-derived cerebral and somatic/renal regional saturations can predict survival by analyzing relationships between standard hemodynamic measures, direct and NIRS measures of saturation, and outcome.
Journal ArticleDOI
Cerebral Oxygenation During Pediatric Cardiac Surgery Using Deep Hypothermia Circulatory Arrest
TL;DR: Brain oxygenation changed at distinct points during surgery in all ages, reflecting fundamental cerebral responses to hypothermic CPB, ischemia, and reperfusion, consistent with experimental work in animals.
Journal ArticleDOI
Sevoflurane anesthesia and brain perfusion
O. Rhondali,Agnès Pouyau,Aurélie Mahr,Simon Juhel,Mathilde De Queiroz,Khalid Rhzioual-Berrada,Sylvain Mathews,Dominique Chassard +7 more
TL;DR: To assess the impact of sevoflurane and anesthesia‐induced hypotension on brain perfusion in children younger than 6 months, a large number of patients were referred to the neonatal intensive care unit.
Journal ArticleDOI
An International, Multicenter, Observational Study of Cerebral Oxygenation during Infant and Neonatal Anesthesia
Vanessa A. Olbrecht,Justin Skowno,Vanessa Marchesini,Lili Ding,Yifei Jiang,Christopher G. Ward,Gaofeng Yu,Huacheng Liu,Bernadette Schurink,Laszlo Vutskits,Jurgen C. de Graaff,Francis X. McGowan,Britta S. von Ungern-Sternberg,C D Kurth,Andrew Davidson +14 more
TL;DR: Mild and moderate low cerebral oxygenation occurred frequently, whereas severe low cerebral saturation was uncommon, and low mean arterial pressure was common and not well associated withLow cerebral saturation.
Journal ArticleDOI
Impact of sevoflurane anesthesia on brain oxygenation in children younger than 2 years.
O. Rhondali,Simon Juhel,Sylvain Mathews,Quentin Cellier,François-Pierrick Desgranges,Aurélie Mahr,Mathilde De Queiroz,Agnès Pouyau,Khalid Rhzioual-Berrada,Dominique Chassard +9 more
TL;DR: To assess the impact of sevoflurane and anesthesia‐induced hypotension on brain oxygenation in children younger than 2 years, a large number of patients were referred to the neonatal intensive care unit.
References
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Journal ArticleDOI
Splanchnic‐cerebral oxygenation ratio as a marker of preterm infant blood transfusion needs
TL;DR: The splanchnic‐cerebral oxygenation ratio (SCOR) provides insight into overall tissue oxygen sufficiency and can be determined using near‐infrared spectroscopy (NIRS), and the usefulness of SCOR as a marker for transfusion need in preterm infants was assessed.
Journal ArticleDOI
Intraoperative hypotension and patient outcome: does "one size fit all?".
TL;DR: The current study and data from others draw important attention to the fact that blood pressure management during surgery might be a factor that can be modified as a means for improving patient outcomes, and an empiric definition of intraoperative Hypotension and Patient Outcome is derived.
Journal ArticleDOI
Predictive value of near-infrared spectroscopy on neurodevelopmental outcome after surgery for congenital heart disease in infancy
TL;DR: In a contemporary cohort of infants undergoing surgery for congenital heart disease, neurodevelopmental outcomes at 2 years of age are largely influenced by patient-related characteristics and the predictive value of NIRS remains unclear.
Journal ArticleDOI
Near infrared spectroscopy monitoring during pediatric aortic coarctation repair.
Richard J. Berens,Eckehard A. E. Stuth,Frederick A. Robertson,Robert D.B. Jaquiss,George M. Hoffman,Todd J. Troshynski,Susan R. Staudt,Joseph R. Cava,James S. Tweddell,S. Bert Litwin +9 more
TL;DR: Near infrared spectroscopy measures regional tissue oxygenation continuously and noninvasively and may allow assessment of changes in regional perfusion in real time.
Journal ArticleDOI
Regional differences in tissue oxygenation during cardiopulmonary bypass for correction of congenital heart disease in neonates and small infants: Relevance of near-infrared spectroscopy
Mathias Redlin,Andreas Koster,Michael Huebler,Wolfgang Boettcher,Nicole Nagdyman,Roland Hetzer,Hermann Kuppe,Wolfgang M. Kuebler +7 more
TL;DR: In neonates and small infants undergoing cardiac surgery with cardiopulmonary bypass, considerable regional differences exist in venous oxygen saturation, and near-infrared spectroscopic monitoring of regional tissue oxygenation yields additional information on regional oxygenation.
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