Journal ArticleDOI
Near-infrared spectroscopy: exposing the dark (venous) side of the circulation.
John P. Scott,George M. Hoffman +1 more
TLDR
Near‐infrared spectroscopy provides noninvasive continuous access to the venous side of regional circulations that can approximate organ‐specific and global measures to facilitate the detection of circulatory abnormalities and drive goal‐directed interventions to reduce end‐organ ischemic injury.Abstract:
The safety of anesthesia has improved greatly in the past three decades. Standard perioperative monitoring, including pulse oximetry, has practically eliminated unrecognized arterial hypoxia as a cause for perioperative injury. However, most anesthesia-related cardiac arrests in children are now cardiovascular in origin, and standard monitoring is unable to detect many circulatory abnormalities. Near-infrared spectroscopy provides noninvasive continuous access to the venous side of regional circulations that can approximate organ-specific and global measures to facilitate the detection of circulatory abnormalities and drive goal-directed interventions to reduce end-organ ischemic injury.read more
Citations
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Journal ArticleDOI
Postoperative Cerebral and Somatic Near-Infrared Spectroscopy Saturations and Outcome in Hypoplastic Left Heart Syndrome
George M. Hoffman,George M. Hoffman,Nancy S. Ghanayem,John P. Scott,John P. Scott,James S. Tweddell,Michael E. Mitchell,Michael E. Mitchell,Kathleen A. Mussatto +8 more
TL;DR: Test the hypothesis that near-infrared spectroscopy (NIRS)-derived cerebral and somatic/renal regional saturations can predict survival by analyzing relationships between standard hemodynamic measures, direct and NIRS measures of saturation, and outcome.
Journal ArticleDOI
Cerebral Oxygenation During Pediatric Cardiac Surgery Using Deep Hypothermia Circulatory Arrest
TL;DR: Brain oxygenation changed at distinct points during surgery in all ages, reflecting fundamental cerebral responses to hypothermic CPB, ischemia, and reperfusion, consistent with experimental work in animals.
Journal ArticleDOI
Sevoflurane anesthesia and brain perfusion
O. Rhondali,Agnès Pouyau,Aurélie Mahr,Simon Juhel,Mathilde De Queiroz,Khalid Rhzioual-Berrada,Sylvain Mathews,Dominique Chassard +7 more
TL;DR: To assess the impact of sevoflurane and anesthesia‐induced hypotension on brain perfusion in children younger than 6 months, a large number of patients were referred to the neonatal intensive care unit.
Journal ArticleDOI
An International, Multicenter, Observational Study of Cerebral Oxygenation during Infant and Neonatal Anesthesia
Vanessa A. Olbrecht,Justin Skowno,Vanessa Marchesini,Lili Ding,Yifei Jiang,Christopher G. Ward,Gaofeng Yu,Huacheng Liu,Bernadette Schurink,Laszlo Vutskits,Jurgen C. de Graaff,Francis X. McGowan,Britta S. von Ungern-Sternberg,C D Kurth,Andrew Davidson +14 more
TL;DR: Mild and moderate low cerebral oxygenation occurred frequently, whereas severe low cerebral saturation was uncommon, and low mean arterial pressure was common and not well associated withLow cerebral saturation.
Journal ArticleDOI
Impact of sevoflurane anesthesia on brain oxygenation in children younger than 2 years.
O. Rhondali,Simon Juhel,Sylvain Mathews,Quentin Cellier,François-Pierrick Desgranges,Aurélie Mahr,Mathilde De Queiroz,Agnès Pouyau,Khalid Rhzioual-Berrada,Dominique Chassard +9 more
TL;DR: To assess the impact of sevoflurane and anesthesia‐induced hypotension on brain oxygenation in children younger than 2 years, a large number of patients were referred to the neonatal intensive care unit.
References
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Journal ArticleDOI
Anaesthesiology as a model for patient safety in health care.
TL;DR: It is widely believed that anaesthesia is safer than ever owing to many different types of solutions to safety problems, and solution strategies have included incorporating new technologies, standards, and guidelines, and addressing problems relating to human factors and systems issues.
Journal ArticleDOI
Anesthesia-related cardiac arrest in children: initial findings of the Pediatric Perioperative Cardiac Arrest (POCA) Registry.
Jeffrey P. Morray,Jeremy M. Geiduschek,Chandra Ramamoorthy,Charles M. Haberkern,Alvin Hackel,Robert A. Caplan,Karen B. Domino,Karen L. Posner,Frederick W. Cheney +8 more
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Journal ArticleDOI
Monitoring tissue oxygen availability with near infrared spectroscopy (NIRS) in health and disease.
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Journal ArticleDOI
Randomized evaluation of pulse oximetry in 20,802 patients: II. Perioperative events and postoperative complications.
J. T. Moller,N. W. Johannessen,Kurt Espersen,Odd Ravlo,Bente D. Pedersen,Per Jensen,Niels H. Rasmussen,Lars S. Rasmussen,Tom Pedersen,Jeffrey B. Cooper,Joachim S. Gravenstein,Bent Chraemmer-Jørgensen,Mogens Djernes,F. Wiberg-Jørgensen,Lars Heslet,Sophus H. Johansen +15 more
TL;DR: The authors describe the effect of pulse oximetry monitoring on the frequency of unanticipated perl-operative events, changes In patient care, and the rate of postoperative complications in a prospective randomized study in Denmark.
Journal ArticleDOI
Oxygen Saturation and Outcomes in Preterm Infants
Ben Stenson,William Tarnow-Mordi,Brian A Darlow,John Simes,Edmund Juszczak,Lisa M. Askie,Malcolm R. Battin,Ursula Bowler,Roland S. Broadbent,Pamela Cairns,Peter G Davis,Sanjeev Deshpande,Mark Donoghoe,Lex W. Doyle,Brian Fleck,Alpana Ghadge,Wendy Hague,Henry L. Halliday,Michael Hewson,Andrew J. King,Adrienne Kirby,Neil Marlow,Michael P. Meyer,Colin J Morley,Karen Simmer,Win Tin,Stephen P. Wardle,Peter Brocklehurst +27 more
TL;DR: Targeting an oxygen saturation below 90% with the use of current oximeters in extremely preterm infants was associated with an increased risk of death.
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