Journal ArticleDOI
Neue Alkaloide aus Rauwolfia Serpentina
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TLDR
I m Verlaufe unse re r schon sei t l~ngerer Zeit im Gange bef ind l ichen U n t e r s u c h u n g e l l fiber die Reil la lkaloide der Rauwol f i a Se rpen t ina h a b e n wir zwei lleue Stoffe aufgefulldell.Abstract:
I m Verlaufe unse re r schon sei t l~ngerer Zeit im Gange bef ind l ichen U n t e r s u c h u n g e l l fiber die Reil la lkaloide der Rauwol f i a Se rpen t ina h a b e n wir zwei lleue Stoffe aufgefulldell , die b i sher noch n i ch t besehr ieben wurden . Es h a n d e l t s ich u m zwei S u b s t a n z e n I und II , die in eiller g e m e i n s a m e n Frakt ion m i t d e m seda t iv w i rkenden Pr inz ip der Droge, d e m Reserp in , vorkommel l . Von e iner N a m e n g e b u l l g wollen wir absehen , bis ihre even tue l l e V e r w a n d t s c h a f t m i t schon bek a n n t e n Stoffen wei ter gekl/irt ist. Die p h y s i k o e h e m i s c h e n D a t e n s ind :read more
Citations
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Journal ArticleDOI
Rauwolfia Serpentina in the Treatment of High Blood Pressure A Review of the Literature
TL;DR: The whole subject of Rauwolfia serpentina therapy in hypertension has been reviewed up to the present time, including discussions on the history of the plant, its various species and types, nomenclature, geographic distribution, chemistry, pharmacologic actions and clinical studies, reported from all over the world.
Journal ArticleDOI
The alkaloids of Rauwolfia serpentina benth
TL;DR: Active chemical and pharmacological interest in R. serpentina has resulted in the discovery of several new alkaloids, and the isolation by Muller, Schlittler, and Bein of reserpine, an alkaloid with pronounced hypotensive and sedative activity, has lent further impetus to the pharmacological and chemical study of the alkal steroids of R. Serpentina.
Journal ArticleDOI
Reserpinin, ein neues Alkaloid ausRauwolfia serpentina Benth
TL;DR: Reserpinine, a minor alkaloid of Rauwolfia serpentina Benth, has been isolated, and its structural formula is proposed.
Journal ArticleDOI
Die Isolierung weiterer Alkaloide aus Rauwolfia serpentina Benth. 3. Mitteilung über Rauwolfia-Alkaloide
TL;DR: In this article, Thebain, Papaverin, Yohimbin, Reserpsaure-methylester und eines Alkaloids der Zusammensetzung C22H26O4N2 (Alkaloid C) aus den Wurzeln von Rauwolfia serpentina Benth.
Journal ArticleDOI
Effects of raubasine stereoisomers on pre- and postsynaptic α-adrenoceptors in the rat vas deferens
TL;DR: Results indicate that: akuammigine is a very weak antagonist at pre‐ and postsynaptic sites; raubasine acts preferentially at post synapse sites; tetrahydroalstonine isA highly selective presynaptic α‐adrenoceptor blocking agent.
References
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Journal ArticleDOI
On the constitution of reserpine.
TL;DR: Durch alkalische Hydrolyse wird Reserpin in Reserpinsäure, 3,4,5-Trimethoxybenzoesäure und Methanol gespalten anderer Spaltstücken wieder resynthetisieren.