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Journal ArticleDOI

Neue Alkaloide aus Rauwolfia Serpentina

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TLDR
I m Verlaufe unse re r schon sei t l~ngerer Zeit im Gange bef ind l ichen U n t e r s u c h u n g e l l fiber die Reil la lkaloide der Rauwol f i a Se rpen t ina h a b e n wir zwei lleue Stoffe aufgefulldell.
Abstract
I m Verlaufe unse re r schon sei t l~ngerer Zeit im Gange bef ind l ichen U n t e r s u c h u n g e l l fiber die Reil la lkaloide der Rauwol f i a Se rpen t ina h a b e n wir zwei lleue Stoffe aufgefulldell , die b i sher noch n i ch t besehr ieben wurden . Es h a n d e l t s ich u m zwei S u b s t a n z e n I und II , die in eiller g e m e i n s a m e n Frakt ion m i t d e m seda t iv w i rkenden Pr inz ip der Droge, d e m Reserp in , vorkommel l . Von e iner N a m e n g e b u l l g wollen wir absehen , bis ihre even tue l l e V e r w a n d t s c h a f t m i t schon bek a n n t e n Stoffen wei ter gekl/irt ist. Die p h y s i k o e h e m i s c h e n D a t e n s ind :

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Citations
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Journal ArticleDOI

Rauwolfia Serpentina in the Treatment of High Blood Pressure A Review of the Literature

TL;DR: The whole subject of Rauwolfia serpentina therapy in hypertension has been reviewed up to the present time, including discussions on the history of the plant, its various species and types, nomenclature, geographic distribution, chemistry, pharmacologic actions and clinical studies, reported from all over the world.
Journal ArticleDOI

The alkaloids of Rauwolfia serpentina benth

TL;DR: Active chemical and pharmacological interest in R. serpentina has resulted in the discovery of several new alkaloids, and the isolation by Muller, Schlittler, and Bein of reserpine, an alkaloid with pronounced hypotensive and sedative activity, has lent further impetus to the pharmacological and chemical study of the alkal steroids of R. Serpentina.
Journal ArticleDOI

Reserpinin, ein neues Alkaloid ausRauwolfia serpentina Benth

TL;DR: Reserpinine, a minor alkaloid of Rauwolfia serpentina Benth, has been isolated, and its structural formula is proposed.
Journal ArticleDOI

Die Isolierung weiterer Alkaloide aus Rauwolfia serpentina Benth. 3. Mitteilung über Rauwolfia-Alkaloide

A. Hofmann
TL;DR: In this article, Thebain, Papaverin, Yohimbin, Reserpsaure-methylester und eines Alkaloids der Zusammensetzung C22H26O4N2 (Alkaloid C) aus den Wurzeln von Rauwolfia serpentina Benth.
Journal ArticleDOI

Effects of raubasine stereoisomers on pre- and postsynaptic α-adrenoceptors in the rat vas deferens

TL;DR: Results indicate that: akuammigine is a very weak antagonist at pre‐ and postsynaptic sites; raubasine acts preferentially at post synapse sites; tetrahydroalstonine isA highly selective presynaptic α‐adrenoceptor blocking agent.
References
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Journal ArticleDOI

On the constitution of reserpine.

TL;DR: Durch alkalische Hydrolyse wird Reserpin in Reserpinsäure, 3,4,5-Trimethoxybenzoesäure und Methanol gespalten anderer Spaltstücken wieder resynthetisieren.
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