Journal ArticleDOI
On the constitution of reserpine.
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Durch alkalische Hydrolyse wird Reserpin in Reserpinsäure, 3,4,5-Trimethoxybenzoesäure und Methanol gespalten anderer Spaltstücken wieder resynthetisieren.Abstract:
Durch alkalische Hydrolyse wird Reserpin in Reserpinsaure, 3,4,5-Trimethoxybenzoesaure und Methanol gespalten. Das Esteralkaloid liess sich aus diesen Spaltstucken wieder resynthetisieren.read more
Citations
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Journal ArticleDOI
Die Konstitution des Reserpins. 8. Mitteilung über Rauwolfia-Alkaloide
L. Dorfman,A. Furlenmeier,Charles F. Huebner,R. Lucas,H. B. MacPhillamy,J. M. Mueller,E. Schlittler,Robert Schwyzer,A. F. St. André +8 more
TL;DR: Reserpine, C33H40O9N2, has been isolated from Rauwolfia serpentina Benth as discussed by the authors and is an ester alkaloid yielding reserpic acid, 3,4,5-trimethoxybenzoic acid and methanol on hydrolysis.
Book ChapterDOI
Binding of Some Biogenic Amines in Tissues
TL;DR: This chapter discusses the binding of some biogenic amines in tissues and encompasses binding in its widest sense, although no attempt is made to cover the biosynthesis of the amines or the catabolic enzymes.
Journal ArticleDOI
The vesicular monoamine transporter 2: An underexplored pharmacological target
TL;DR: A renewed focus on these transporters as potential targets is timely and necessary because novel compounds and methods are now making high throughput screening for function of these vesicular neurotransmittertransporters possible.
Journal ArticleDOI
The alkaloids of Rauwolfia serpentina benth
TL;DR: Active chemical and pharmacological interest in R. serpentina has resulted in the discovery of several new alkaloids, and the isolation by Muller, Schlittler, and Bein of reserpine, an alkaloid with pronounced hypotensive and sedative activity, has lent further impetus to the pharmacological and chemical study of the alkal steroids of R. Serpentina.
References
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Journal ArticleDOI
Reserpin, der sedative Wirkstoff ausRauwolfia serpentina Benth
TL;DR: The sedative principle of Rauwolfia serpentina Benth has been isolated in pure crystalline form and its chemistry and pharmacology has been studied as discussed by the authors, and its properties and properties have been investigated.
Journal ArticleDOI
Zur Pharmakologie des Reserpin, eines neuen Alkaloids ausRauwolfia Serpentina Benth
TL;DR: There is evidence, that central portions of the sympathetic system are inhibited by Reserpin, a new, highly active alcaloid from Rauwolfia serpentina benth.